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G bg

B. A. C. Mammals. Mammals. Yeast. Mating factor receptor. LPA receptor. LPA or RA receptor. G bg. G bg. G a 12/13. scaffold Ste5. scaffold KSR1. scaffold JLP. MAP3K MEKK3 ASK1?. MAP3K Ste11. MAP3K Raf1. MAP2K MEK1/2. MAPK ERK1/2. MAP2K MKK4. MAP2K Ste7. MAPK

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G bg

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  1. B A C Mammals Mammals Yeast Mating factor receptor LPA receptor LPA or RA receptor Gbg Gbg Ga12/13 scaffold Ste5 scaffold KSR1 scaffold JLP MAP3K MEKK3 ASK1? MAP3K Ste11 MAP3K Raf1 MAP2K MEK1/2 MAPK ERK1/2 MAP2K MKK4 MAP2K Ste7 MAPK Fus3 MAPK JNK Mating signaling Downstream signaling Transcription factors (Myc, Max)

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