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T47D. Hs 578t. EpCAM high. EpCAM low. MCF-7. MDA-MB-231. EMT. shRNA ns-crtl. Cytokeratin high. shRNA EpCAM. Vimentin high. Control. EpCAM. EpCAM. crtl. crtl. shRNA. T. T. CAM. CAM. T. T. T. CAM. CAM. CAM. CAM. T. CAM. • proangiogenic • invasive.
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T47D Hs 578t EpCAM high EpCAM low MCF-7 MDA-MB-231 EMT shRNA ns-crtl Cytokeratinhigh shRNA EpCAM Vimentinhigh Control EpCAM EpCAM crtl crtl shRNA T T CAM CAM T T T CAM CAM CAM CAM T CAM •proangiogenic • invasive • less angiogenic • less invasive • proangiogenic • invasive • less invasive • immune responses Fig.8