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Cellular Respiration Part 1

Cellular Respiration Part 1. Harvesting Chemical Energy from Glucose. Energy Released. ATP. Glycolysis. e - Carriers. O 2 present. 2 CO 2. e - Carriers. e -. e -. ATP. e -. 4 CO 2. Electron Transport Chain. Citric Acid Cycle. e - Carriers. 2 H +. ATP.

norman-melton
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Cellular Respiration Part 1

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  1. Cellular RespirationPart 1 Harvesting Chemical Energy from Glucose

  2. EnergyReleased ATP Glycolysis e- Carriers O2 present 2 CO2 e- Carriers e- e- ATP e- 4 CO2 Electron Transport Chain Citric Acid Cycle e- Carriers 2 H+ ATP Releasing Energy From Glucose EnergyReleased Glucose (6C) 2 X Pyruvate (3C) Cytoplasm Mitochondrion 2 X Acetyl-CoA (2C) H2O ½ O2

  3. Electron carrier NAD+ accepts two electrons and one proton to become NADH Redox Reactions • Reduction: Gain of one or more electrons or hydrogen atoms • Oxidation: Loss of one or more electrons or hydrogen atoms

  4. Energy Yield of Glucose Oxidation • C6H12O6 + 6O2 6CO2 + 6H2O + energy • 40% of released energy captured in ATP • Involves two electron carriers • NAD+ + 2H+ + 2 electrons  NADH + H+ • FAD + 2H+ + 2 electrons  FADH2 • Electrons donated to Electron Transport Chain to produce ATP

  5. Glucose (6C) 2 ATP 4 ATP Set of 10 reactions 2 NAD+ 2 NADH 2 X Pyruvate (3C) C C C C C C C C C C C C Overview of Glycolysis Net gain of 2 ATP Occurs in cytoplasm under anaerobic conditionsGluconeogenesis can convert pyruvate glucose

  6. Energy Investment Reactions of Glycolysis Step 1

  7. Energy Investment Reactions of Glycolysis Step 2

  8. Energy Investment Reactions of Glycolysis Step 3

  9. Energy Investment Reactions of Glycolysis--Step 4

  10. Energy Investment Reactions of Glycolysis Step 5

  11. 1. NAD+ 2. G3P 3. BPG 4. NADH A. Which undergoes oxidation? B. Which undergoes reduction? Energy-Harvesting Reactions of Glycolysis Step 6

  12. Energy-Harvesting Reactions of Glycolysis Step 7

  13. Energy-Harvesting Reactions of Glycolysis Step 8

  14. Energy-Harvesting Reactions of Glycolysis Step 9

  15. Energy-Harvesting Reactions of Glycolysis Step 10

  16. 2 X 2 2 2 +2 2 2 X 1. NAD+ 2. Acetyl-CoA 3. Pyruvate 4. NADH A. Which molecule is an oxidizing agent? B. Which is a reducing agent? Pyruvate Oxidation Occurs in the Mitochondrial MatrixNot Reversible, Cannot convert 2C3C for pyruvate  glucose pathway

  17. 2 X Acetyl-CoA (2C) 6 NADH 2 ADP Citric Acid CycleSet of 8 reactions C 2 FADH2 6 NAD+ 2 ATP 4 CO2 2 FAD C C CoA Overview of the Citric Acid Cycle Electron Transport Chain

  18. Citric Acid CycleStep 1

  19. Citric Acid CycleStep 2

  20. Citric Acid CycleStep 3

  21. Citric Acid CycleStep 4

  22. Citric Acid CycleStep 5

  23. 1. FAD 2. Fumarate 3. Succinate 4. FADH2 A. Which undergoes oxidation? B. Which undergoes reduction? Citric Acid CycleStep 6

  24. Citric Acid CycleStep 7

  25. Citric Acid CycleStep 8

  26. Free Energy Change for Glucose Oxidation

  27. 2 ATP Net Gain Energy Harvested from Glucose Glucose (Cytoplasm) 4 ATP Glycolysis 2 ATP 2 Pyruvates 2 NADH (MitochondrialMatrix) 2 CO2 2 NADH Citric AcidCycle 6 NADH 4 CO2 2 FADH2 2 ATP (InnerMembrane) Water Electron TransportSystem 32 ATP Oxygen

  28. Where is the Citric Acid cycle located? Where does glycolysis occur? Where is CO2 produced? Where is the electron transport chain located? Cytoplasm Mitochondrion Both Cytoplasm and Mitochondrion Neither the Cytoplasm nor Mitochondrion Applying Your Knowledge

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