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Human Reproduction

Human Reproduction. Reproductive hormones. LH & FSH. Testosterone from testes functions sperm production 2° sexual characteristics Estrogen from ovaries functions egg production prepare uterus for fertilized egg 2° sexual characteristics. testes or ovaries. Male reproductive system.

octavius-roberts
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Human Reproduction

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  1. Human Reproduction

  2. Reproductive hormones LH &FSH • Testosterone • from testes • functions • sperm production • 2° sexual characteristics • Estrogen • from ovaries • functions • egg production • prepare uterus for fertilized egg • 2° sexual characteristics testesorovaries

  3. Male reproductive system • Sperm production • over 100 million produced per day! • ~2.5 million released per drop!

  4. Male reproductive system • Testicles • produces sperm & hormones • Scrotum • sac that holds testicles outside of body • Epididymis • where sperm mature • Vas deferens • tubes for sperm to travel from testes to penis • Prostate, seminal vesicles, Cowper’s (bulbourethal) glands • nutrient rich fluid to feed & protect sperm • buffer to counteract acids in vagina

  5. seminiferous tubule Male reproductive system • Testes & epididymis • sperm production & maturation • Glands • seminal vesicles, prostate, bulbourethal • produce seminal fluid = nutrient-rich sperm spermatocytes

  6. Spermatogenesis Testis Epididymis Germ cell (diploid) Coiled seminiferous tubules 1° spermatocyte (diploid) MEIOSIS I 2° spermatocytes (haploid) MEIOSIS II Vas deferens Spermatids (haploid) Spermatozoa Cross-section of seminiferous tubule

  7. Female reproductive system

  8. Female reproductive system • Ovaries • produces eggs & hormones • Uterus • nurtures fetus; lining builds up each month • Fallopian tubes • tubes for eggs to travel from ovaries to uterus • Cervix • opening to uterus, dilates 10cm (4 inches) for birthing baby • Vagina • birth canal for birthing baby

  9. Female reproductive system

  10. LH Menstrual cycle FSH Hypothalamus egg development ovulation = egg release GnRH corpus luteum Pituitary FSH & LH estrogen progesterone Ovaries lining of uterus estrogen Body cells days 0 7 14 21 28

  11. Egg maturation in ovary • Corpus luteum • produces progesterone to maintain uterine lining

  12. Female hormones • FSH & LH • release from pituitary • stimulates egg development & hormone release • peak release = release of egg (ovulation) • Estrogen • released from ovary cells around developing egg • stimulates growth of lining of uterus • lowered levels = menstruation • Progesterone • released from “corpus luteum” in ovaries • cells that used to take care of developing egg • stimulates blood supply to lining of uterus • lowered levels = menstruation

  13. Oogenesis • What is the advantage of this development system? Meiosis 1 completed during egg maturation ovulation Meiosis 2 completed triggered by fertilization

  14. Fertilization

  15. Fertilization • Joining of sperm & egg • sperm head enters egg

  16. Cleavage • Repeated mitotic divisions of zygote • 1st step to becoming multicellular • unequal divisions establishes body plan • different cells receive different portions of egg cytoplasm & therefore different regulatory signals

  17. Cleavage • zygote  morula  blastula • establishes future development

  18. Gastrulation • Establish 3 cell layers • ectoderm • outer layers • skin, nails, teeth, nerves • mesoderm • blood, bone & muscle • endoderm • inner lining • digestive system ectoderm mesoderm endoderm

  19. Neural groove Notochord Neurulation • 1st organ to form is notochord & nerve chord • develop into nervous system Neural tube

  20. Organogenesis Umbilical blood vessels Mammalian embryo Chorion Bird embryo Amnion Yolk sac Allantois Fetal blood vessels Placenta Maternal blood vessels

  21. Placenta • Materials exchange across membranes

  22. Human fetal development 4 weeks 7 weeks

  23. Sex determination Zygote Sperm Develop in early embryo Y Testes XY Ovum X SRY Seminiferous tubules Indifferent gonads Leydig cells No SRY X Ovaries Ovum XX (Follicles do not develop until third trimester) X Sperm Zygote

  24. Human fetal development 10 weeks

  25. Human fetal development 12 weeks 20 weeks

  26. Human fetal development • The fetus just spends much of the 2nd & 3rd trimesters just growing …and doing various flip-turns & kicks inside amniotic fluid Week 20

  27. Human fetal development • 24 weeks (6 months; 2nd trimester) fetus is covered with fine, downy hair called lanugo. Its skin is protected by a waxy material called vernix

  28. Human fetal development • 30 weeks (7.5 months) umbilical cord

  29. Getting crowded in there!! • 32 weeks (8 months) The fetus sleeps 90-95% of the day & sometimes experiences REM sleep, an indication of dreaming

  30. Hormone induction Birth positive feedback

  31. Birth (36 weeks) Intestine Placenta Umbilical cord Wall of uterus Bladder Cervix Vagina

  32. The end of the journey!

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