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Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus

Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus. Brian S. Boxer Wachler, M.D. Lorelei L. Vicente, M.D. BEVERLY HILLS , CA. Disclosure.

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Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus

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  1. Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus Brian S. Boxer Wachler, M.D. Lorelei L. Vicente, M.D. BEVERLY HILLS , CA

  2. Disclosure Financial declaration/conflict of interest: Dr. Boxer Wachler is consultant to Addition Technology and Staar Surgical. Dr. Vicente has no financial interest in the subject matter of this paper.

  3. Purpose To analyze long-term results of patients with keratoconus who had trans-epithelial corneal collagen crosslinking for ectasia.

  4. Methods • 7 eyes of 4 patients • Mean age: 39 +/- 11 years • Trans-epithelial Crosslinking using 0.1 % riboflavin with 0.5% carboxymethylcellulose (RF-CMC) andTetracaine

  5. Methods Comparison of baseline and follow-up exam of visual parameters after 3 years • UCVA • BCVA • Manifest spherical equivalent (SE) • Refractive cylinder • Topography (NIDEK ARK-9000 OPD-SCAN Refractive Power/Corneal Analyser (Marco, Jacksonville, FL)

  6. Trans-Epithelial Crosslinking • Pretreatment with Tetracaine and RF-CMC • Instilled one drop after another every 5 minutes for 15 minutes • Trans-Epithelial Crosslinking Protocol RF-CMC (q 3 min.) & Tetracaine (q 10 min.) for 30 mins. • Applied via soppy, wet surgical sponges (Merocel eye spears, Medtronic, Jacksonville, FL) • Ultraviolet-A light (3.0 mW/cm2 at 370 nm)

  7. Results

  8. Results

  9. Conclusion Preoperative visual parameters remained stable after Trans-Epithelial Crosslinking with 0.1% riboflavin w/ 0.5% CMC (RF-CMC)

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