A Clinical profile of optic neuritis in a tertiary center in Northern India FP1550

1. A Clinical profile of optic neuritis in a tertiary center in Northern IndiaFP1550 Dr. Manisha Nada Dr. S.V. Singh Dr. V.K.Dhull Dr. C.S.Dhull Regional Institute of Ophthalmology, PGIMS, Rohtak.

2. Optic neuritis It is an Inflammatory demyelinating disease of optic nerve resulting in loss of vision with variable recovery. Presenting features Decreased vision Pain Visual field defects Color vision defects

3. Aim of the present study To study clinical profile of Optic Neuritis cases presenting at PGIMS, Rohtak over 3 years period (2007-2010) To evaluate efficacy of intravenous steroids therapy in management of Optic Neuritis.

4. Material & Methods Pulse therapy included I/V methyl prednisolone 1gm/day for 3 days followed by oral prednisolone for 11 days & tapering subsequently. A retrospective study of 54 patients with optic neuritis. Detailed history for symptoms of optic neuritis was recorded. Complete ocular examination was done . Relevant neurological and systemic examination was done. MRI of brain & orbit. Pulse therapy was given after confirmation of diagnosis.

5. Material & Methods- Follow-up Follow up was done till three months. Visual acuity recording was done with Snellen’s chart. Colour vision was tested with Ishihara plates. Visual field – Humphrey field analyzer (Diffuse depression, ceco central scotoma, central scotoma, arcuate, paracentral scrotomas). VEP testing was done at presentation & follow up.

6. Results

7. Presenting Complaints

8. Associated systemic illness

9. Pie Charts showing improvement in visual acuity

10. VEP-Follow up Two weeks Presentation

11. Conclusion Optic neuritis was most commonly of idiopathic origin and associated illness was rarely seen. Females were more commonly affected. Most common symptom was loss of central and peripheral visual acuity along with painful ocular motility. IVMP regimen lead to good visual recovery.

12. THANKS