1 / 65

F 2006 BIOC 3405

F 2006 BIOC 3405. 11-09-06. Carbohydrates. C n (H 2 O) n primarily Mono- Oligo- Polysaccharides. Representations. Fisher projections Haworth structures More realistic structural formulae. Aldoses and Ketoses. Family of structures Most D-structures survey. Reducing Sugars.

radwan
Download Presentation

F 2006 BIOC 3405

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. F 2006 BIOC 3405 11-09-06

  2. Carbohydrates • Cn(H2O)n primarily • Mono- • Oligo- • Polysaccharides

  3. Representations • Fisher projections • Haworth structures • More realistic structural formulae

  4. Aldoses and Ketoses • Family of structures • Most D-structures • survey

  5. Reducing Sugars • Aldehyde + Cu2+ Acid + Cu+ Glucose + Cu2+ gluconic acid + Cu+ Sucrose + Cu2+  no reaction

  6. Mutarotation of glucose • Prepare pure +glucose (Say -D-glucopyranose) • Dissolve in H2O • In time, optical rotation diminishes. • Found to be a mixture (melting point lower) • What has happened? • Answer: “Mutarotation”

  7. A glycoside

  8. Naming oligos • Config of anomeric C of non-reducing monosaccharide • Name of monosaccharide, with 5 or 6 ring word (furan- or pyran-) and -osyl • Dash • Hookup, with , in parentheses • Dash • Name of reducing monosaccharide, with –ose Example: maltose -D-glucopyranosyl-(14)-D-glucopyranose

  9. Carbon 4 is epimeric Shorthand notation

  10. Nonreducing disaccharides • Config of anomeric carbon of either sugar • Name with furan- or pyran- of sugar and osyl ending • Dash • Linkage with arrow within parentheses • Config of other sugar’s anomeric C • Name with –oside ending Example: sucrose -D-glucopyranosyl-(12)--D-fructofuranoside

  11. Found in hemolymph

  12. polysaccharides

  13. peptidoglycans glycosaminoglycans hyaluronate agarose Cellulose Glycogen Starch chitin

  14. amylopectin

  15. cellulose

  16. Note extension in two dimensions

  17. Fungus contains cellulase

  18. (14) linkage Chitin N-acetyl-D-glucopyranosamine (GlcNac)

  19. Chitin

  20. 3-D structure of polysacharrides • cf with proteins • Dihedral angles ,

More Related