1 / 80

F 2006 BIOC 3405

F 2006 BIOC 3405. 11-16-06. Nucleotides. Nucleoside phosphate Base and ribose (or deoxyribose) Pyrimidine Purine. Minor Bases. Nomenclature Substituent on ring Substituent on N on ring. Reason for instability of RNA. Bases. Slightly basic Highly conjugated UV absorbers

verlee
Download Presentation

F 2006 BIOC 3405

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. F 2006 BIOC 3405 11-16-06

  2. Nucleotides • Nucleoside phosphate • Base and ribose (or deoxyribose) • Pyrimidine • Purine

  3. Minor Bases • Nomenclature • Substituent on ring • Substituent on N on ring

  4. Reason for instability of RNA

  5. Bases • Slightly basic • Highly conjugated • UV absorbers • Nearly flat (Purines slightly out of plane) • Insoluble at normal pH • Hydrophobic stacking minimizes interaction with water • Capable of H-bond formations in complementary ways

  6. Schreiner U, 1977-1990

  7. Chargaff’s Rules • DNA from different species have different base compositions • DNA from same species (or tissues from same individual) have the same composition • Base composition constant over time, environmental conditions, state of organism • A=T and G=C

More Related