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Innovating for the Future

Innovating for the Future. AGRI OUTLOOK 2007. Kobus Lindeque Monsanto Company. Corn Yields Continue to Advance, Tremendous Gains Made Over Last Ten Years. Actual Breeding Plus Cultural Practice Gain. Source: March 2006. Crop Science. Ref# 46:528-543. 70. Soybean. 60. Maize. 50. Cotton.

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Innovating for the Future

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  1. Innovating for the Future AGRI OUTLOOK 2007 Kobus Lindeque Monsanto Company

  2. Corn Yields Continue to Advance, Tremendous Gains Made Over Last Ten Years • Actual Breeding Plus Cultural Practice Gain Source: March 2006. Crop Science. Ref# 46:528-543

  3. 70 Soybean 60 Maize 50 Cotton Canola 40 30 20 10 0 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 Global Area of Biotech Crops, 1996 to 2006: By Crop (Million Hectares) Total hectares planted - 102 Million Source: Clive James, 2006

  4. 80 Herbicide Tolerance 70 Insect Resistance 60 Herb Tolerance/Insect resistance 50 40 30 20 10 0 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 Figure 6. Global Area of Biotech Crops, 1996 to 2006: By Trait (Million Hectares) Total hectares planted - 102 Million Source: Clive James, 2006

  5. Maize Hectares planted under biotechnology in South Africa 5,1% 2,4% 3,8% 7,5% 29,4% 16,9% 1,6% 42,3% Hectares planted (000)

  6. Biotech Crops Bringing Benefits to Agriculture, Growers and the Environment • The Global Impact of Biotechnology Productivity $6.2B global value of biotech crops in 2006 Economic Return $27B cumulative net economic benefits at the farm level Pesticide Reduction 224M Kg (~500M lbs), 6.9% reduction Greenhouse Gas Emissions Reduced >9B Kg Carbon Dioxide Emission in 2005 Equal to removing 4M cars from the road for a year Source: Brookes, AgBioForum, 9(3),2006 ; NCFAP report, 2005; Ford Runge & Barry Ryan 2005 Pesticides registered by the U.S. Environmental Protection Agency will not cause unreasonable adverse effects to man or the environment when used in accordance with label directions.

  7. Scientific Advancement Resulting inCurrent and Future Yield Enhancement Higher Yielding Nitrogen Utilization Drought Tolerance Herbicide Tolerance Yield Per Acre Increases Insect Protection …and Beyond Early Next Decade Mid Next Decade Commercialized Molecular Breeding Forms the Solid Base to Build in Seed Enhancement Advances Assisting in Protecting and Boosting Yields Commercialized Products Insulate farmers from extreme weather and insect infestations Future Products Boost yield while maximizing the seed for use in feed, food and fuel

  8. Multi-Generational Drought-Tolerant Corn Creates Value Across Multiple Market Segments Drought Tolerant Corn Yield Improvement of Lead Event Under Drought Stress Percent yield difference vs. control 7.3% 10.5% 10.9% 23.2% 9.0% 7.6% 14 12 10 Calera De Tango, Chile 2007 8 Yield Difference (bu/acre) 6 4 • Drought tolerant technology is consistently delivering yield improvements under drought conditions for the fourth season in a ro Not Tested Not Tested 2 0 2004 U.S. 2005U.S. 2006U.S. 2006/07 LAS Hybrid 1: 2004, 4 locations; 2005 5 locs; 2006, 1 loc (20 reps) Hybrid 2: 2004, not tested; 2005, 5 locs, 2006, 3 locs, LAS 2006 3 locs (20 reps)

  9. Building Yield Enhancement By Using Nitrogen Efficiently Nitrogen Utilization Corn Update LEAD NITROGEN UTILIZATION • Industrial scale genomic efforts are generating leads • Lead events show roughly 10% yield increase in multi-location field trials under limiting nitrogen 175 170 165 EVENT 1 EVENT 2 160 YIELDBU/ACRE CONTROL 155 Reduction in Applied Nitrogen 150 145 140 0 40 80 180 NITROGEN INPUT: LBS/ACRE These 2 events show no yield drop off as the Nitrogen application levels decrease from 200 kg/Ha to 45 kg/Ha

  10. Continued growth in Ethanol dryf drives maize prices in the USA 58,5 billion liters needed at end 2009 need addisional 8M hektares Ethanol Capasityt Miillion gallons 4,2 billion liters 15,8 billion liters 21,2 billion liters 2007 2008 2006

  11. Providing Tailored Seed Offerings Necessary to Fuel Ethanol Markets Example: Iowa Ethanol Refineries One of Monsanto’s Future Stacks YieldGard Corn Borer DUBUQUE YieldGard Rootworm SIOUX CITY CEDAR RAPIDS Roundup Ready Corn 2 IOWA CITY AMES Mavera™ High Value Corn DAVENPORT DES MOINES Lysine trait BURLINGTON WET MILL ETHANOL PLANTS UNDER CONSTRUCTION DRAW AREA FOR ETHANOL DRY MILL ETHANOL PLANTS IN PRODUCTION • Maximizing Co-Product Value Ethanol Draw Area 290K corn acres required to supply a 100M gallon dry mill

  12. Increasing Omega-3 for Health Benefits SDA OIL IS MORE STABLE THAN FISH OIL 400 Stabilized 20% SDA 350 300 250 Stabilized Fish Oil Peroxide Value, Meg/Kg 200 150 100 50 0 0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 Days at 55°C • Benefits of Omega-3 TASTE DATA OF STEARIDONIC ACID (SDA) OIL IS SUPERIOR TO FISH OIL 8 6 Taste Rating (0-15 scale) 4 2 A Score of Zero Indicates No Taste 0 Fish Oil Soy Oil SDA Oil

  13. Omega-3 Soybeans Have Met Early Development Targets for Food Application and Field Performance Consistent Agronomic Performance of Omega-3 Soybeans in Field Trials 80 70 60 50 Average Yield (bu/ac) 40 30 20 10 0 U.S. 2004 Argentina 2004-2005 U.S. 2005 Argentina 2005-2006 U.S. 2006 (10 Locations) (15 Locations) (16 Locations) (12 Locations) (12 Locations) OMEGA-3 CONTROL Over 5 growing seasons and 65 locations, no significant yield differences between the Omega-3 lead event and control Omega-3 Soybeans • With soybean oil that would contain 20% stearidonic acid, the intent is for taste, shelf-life and oil stability to be as close to soybean oil as possible

  14. Enhancing Essential Amino Acids in Feed • Mavera™ High Value Corn With Lysine • Enhance level of limiting essential amino acids and corn oil content in feed • Lower cost of animal feed ration • Improve amino acid balance • Increase total energy 2000 Free Lysine Level (in parts per million) Minimum Target 1000 0 South America Result Control U.S. Result

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