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CNS infection

CNS infection . Central Nervous System Infection. Common symptoms: headache, nausea, vomiting , anorexia, restlessness, altered state of consciousness, and irritability ; most are nonspecific

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CNS infection

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  1. CNS infection

  2. Central Nervous System Infection • Common symptoms: headache, nausea, vomiting, anorexia, restlessness, altered state of consciousness, and irritability; most are nonspecific • Common signs: Fever, photophobia, neck pain and rigidity, obtundation, stupor, coma, seizures, and focal neurologic deficit

  3. Diffuse vs Focal CNS infection • Diffuse: Meningitis and Encephalitis • Usually presents with nonspecific symptoms • Nuchal rigidity, Kernig sign, Brudzinski sign • Seizures: • 1st 4 days: no prognostic significance • Persistent after 4 days and difficult to treat: associated with poor prognosis • Altered mental status: irritability, stupor, coma • Focal: Brain abscess • Also presents with nonspecific symptoms • Nystagmus, ipsilateral ataxia and dysmetria, vomiting, and headache

  4. Diagnosis • Diffuse CNS infections: Examination of the Cerebrospinal Fluid obtained by Lumbar Puncture • Brain abscess: relative contraindication to perform lumbar puncture; CT w/ contrast and MRI are the diagnostic studies of choice/most reliable in demonstrating cerebritis and abscess formation • Patient’s case: No lumbar puncture yet; Cranial UTZ indicative of meningitis

  5. Cerebrospinal Fluid Findings in Meningitis

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