1 / 11

Oe sophageal C ancer

Oe sophageal C ancer. Katja Prašek- Kudrna Mentor: A. Žmegač Horvat. Types. Benign (10%) Epithelial Mesenchymal Malignant (90%) Epithelial Mesenchymal Others. Epidemiology. In the top 10 malignant tumors Geographic variability 4 times more frequent in ♂ Elderly. Etiology.

Download Presentation

Oe sophageal C ancer

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. OesophagealCancer Katja Prašek- Kudrna Mentor: A. Žmegač Horvat

  2. Types • Benign (10%) • Epithelial • Mesenchymal • Malignant (90%) • Epithelial • Mesenchymal • Others

  3. Epidemiology • In the top 10 malignant tumors • Geographic variability • 4 times more frequent in ♂ • Elderly

  4. Etiology • Alcohol and smoking • Other carcinogens • Damage of the oesophagus • Deficiency of Mb, Zn and vitamin A • GERD • HPV • Other illnesses

  5. Pathology • Microscopic • Squamous cell cancer • Adenocarcinoma • Macrosopic • Superficial form • Polyp • Ulcer • Infiltrative form

  6. Signs and symptoms • 90% - dysphagia and weight loss • Aspiration pneumonia and cough • Hoarseness • Horner syndrome • Palpableneck lymph nodes • Hypercalcaemia • Bleeding • Infection

  7. Diagnostics • X rays • Oesophagoscopy (histology and cytology) • Endoscopic ultrasound • CT and PET • Bronchoscopy

  8. Prognosis and Treatments • Radiochemotherapy • SURGICAL- total/ partial oesophagostomy • CYTOSTATICS- cisplatin, 5- fluorouracil • PALLIATIVE TREATMENT- stent or laser rechanneling • 5 year survival < 5%

  9. References • Vrhovac, Jakšić, Reiner, Vucelić: Interna medicina, naklada Ljevak, Zagreb 2008 • Robbins: Basic Pathology, Saunders Elsavier, 2007 • http://en.wikipedia.org/wiki/Esophageal_cancer

More Related