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BIO 120 General Biology I

BIO 120 General Biology I. Jaclyn Madden Harford Community College. BIO 120 General Biology I. Lecture 48 students Meets twice per week for 80 minutes Lab 24 students Each student attends one lab per week for 2 hours and 45 minutes.

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BIO 120 General Biology I

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  1. BIO 120 General Biology I Jaclyn Madden Harford Community College

  2. BIO 120 General Biology I • Lecture • 48 students • Meets twice per week for 80 minutes • Lab • 24 students • Each student attends one lab per week for 2 hours and 45 minutes • An introduction to biology (cellular/molecular) for the science major. Basic biological principles common to plants and animals, cell structure and function, biochemical processes, heredity, cell reproduction, and gene expression are presented. Laboratory emphasizes open-ended experimental methods of inquiry.

  3. Course Learning Objectives • Describe the basic anatomical structures and physiological functions of both plant and animal cells. • Explain the four major macromolecules, their building blocks, and functions in biochemical processes of the cell. • Compare and contrast the basic interrelationships between living cells and their internal and external environments. • Describe the processes of DNA replication, protein expression, and gene regulation in prokaryotes and eukaryotes. • Relate the processes involved in cell division with those of inheritance (genetics). • Employ basic laboratory techniques during laboratory investigations to gain a better understanding of the interrelationships of living organisms and the biosphere. • Identify and locate appropriate types of information for review, evaluate the information, and use the information effectively, ethically, and legally. • Recognize ethical issues and practice professional standards common to biologists.

  4. Week 1 Wednesday: Review replication: strip sequence activity (5 min) Lecture on transcription and practice transcription process on board (35 min) Lecture on genetic code and translation and completion of protein sequence on board (35 min) Questions 3-4 of case study (15 minutes) Monday: Review central dogma and present CF case study (10 min) Nucleotide sketch and share (2 min) Brainstorming (2 min) Lecture on replication and practice sequence (50 min) Case study questions 1-2 in groups (15 min) Tuesday: Read chapter 17 through concept 17.4 and complete guided notes; Watch video; Complete quiz on Mastering Biology Thursday – Sunday: Review replication, transcription, and translation Read concept 17.5 in text and complete guided notes Thursday-Sunday: Read chapter 16 and complete guided notes; watch video; Complete quiz on Mastering Biology

  5. Week 2 Monday: Review transcription and translation: sequence strip activity (5 min) Lecture on mutations (15 min) Case study: group review of questions 1-4 and completion of questions 5-8 (60 min) Lab: Genes and ConSequences Wednesday: Lab: Genes and ConSequences Thursday – Sunday: Complete Genes and ConSequences lab report questions Work on presentation (Wednesday lab group) Thursday – Sunday: Review replication, transcription, and translation Read concept 17.5 in text and complete guided notes Complete Genes and ConSequences pre-lab activity Tuesday: Complete Genes and ConSequences lab report questions Work on presentation (Monday lab group)

  6. Applying the Central Dogma: Cystic Fibrosis Case Study • Students will have had an introduction to cystic fibrosis throughout the semester • Cell membrane transport • Genetics • The Applying the Central Dogma: Cystic Fibrosis Case Study • Learning activity and formative assessment • Students will complete the case study in groups in interrupted format • The final product will be turned in for a group grade.

  7. Applying the Central Dogma: Genes and ConSequences Lab • Genes and ConSequences lab (from Carolina Biological Supply) • Students work with the concepts of replication, transcription, and translation while learning bioinformatics skills • Electropherogram used to determine the coding DNA, template DNA, mRNA, and protein sequences • Use NCBI BLAST searches to learn about their proteins. • Students examine how the mutation affects the mRNA and protein sequences. Students use NCBI tools to examine the disorders associated with the mutation • Extension: Students will create and present their own case studies based on their results from the Genes and ConSequences lab

  8. Reflection http://commons.wikimedia.org/wiki/File:Norris_Geyser_Basin,_Yellowstone_National_Park_(7780101904).jpg http://www.craterlakeoregon.org/

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