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Objective for

Objective for. System of Quality of. Measure Life. Team Members. Maja Middleton – Team Leader Kayla Ericson – Communicator Kristin Riching – BSAC Katherine Davis - BWIG. Client Dr. Erwin B. Montgomery M.D. Department of Neurology Advisor Prof. Justin Williams BME Department.

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Objective for

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  1. Objective for

  2. System of Quality of

  3. Measure Life

  4. Team Members Maja Middleton – Team Leader Kayla Ericson – Communicator Kristin Riching – BSAC Katherine Davis - BWIG

  5. Client Dr. Erwin B. Montgomery M.D. Department of Neurology Advisor Prof. Justin Williams BME Department

  6. Problem Statement • Design a system or tool to measure the quality of life for a patient suffering from movement disorders. • The system/device must provide evidence that the quality of life has improved post surgery so that insurance companies will continue to fund deep-brain stimulus rehabilitation.

  7. Quality of Life • Definition: Quality of life is a measure of the means that people live within their own environments in ways that are best for them • Applicable Definition: The ultimate goal of deep brain stimulation surgery is to enable people to live quality lives -- lives that are both meaningful and enjoyed, but are also functional mentally, physically and socially.

  8. Three Aspects of Quality of Life • Mental – Patient’s feelings and attitudes about themselves and their abilities as related to their disease and quality of life • Cognitive assessment (PADLS or MSQOL54) • Physical – Patient’s ability to perform daily tasks • Bluetooth accelerometer • Social – Patient’s daily interactions with society and personal relationships • GPS • All three aspects will be measured pre- and post-surgery

  9. Product Design Specifications

  10. Background Material and Research Movement Disorder Symptoms Rigidity Postural Instability Tremor Bradykinesia / akinesia Slowness Absence of movement Dyskinesia Abnormal, involuntary movement Side effect of drug therapy

  11. Previous Methods • No previous devices for objective measure of movement disorders found besides written questionnaires and doctor judgment. • Doctor observation is becoming less accepted as insurance companies lean toward evidence based medicine

  12. Background Material and Research • Insurance companies only pay for necessary rehabilitation treatments that bring the patient to a normal functioning level for their environment • They continue to fund treatments so long as progress continues • All progress is marked on a scale that relates to daily functions of life • Reaching, lifting, standing, walking, dressing, etc…

  13. Deep Brain Stimulation • For neurologically based movement disorders • Two electrodes implanted in the brain are fed to a pulse generator implanted in the chest • The generator delivers high-frequency electrical stimulation that shuts down nerve cells to allow cells to regain self-control Figure 1: http://www.clevelandclinic.org/neuroscience/techniques/dbs.htm

  14. Physical Design Specifications • Accelerometers • 5 subunits • One for each wrist (2 total) • One for each ankle (2 total) • One on the trunk as a reference • Bluetooth enabled • Allows for wireless messaging of data to the central PDA Depth: 5mm 35 mm 35 mm Figure 2: Top picture - front view; bottom picture – back view http://www.gvu.gatech.edu/ccg/resources/btacc/index.html

  15. Physical Technical Aspects • All accelerometers need to communicate together – done via the PDA and Bluetooth technology • Each signal must be recognized individually by the PDA (X, Y, Z data in ASCII format – number for a character) • Will sample at 20 Hz (Nyquis’ Theorem) • Battery life (Lithium ion) is about 60 hours (840 mAh – 3.7V) • Has A-D conversion

  16. Central Integration Unit • Hewlett Packard - Personal Desktop Assistant (PDA) • Bluetooth enabled PDA • CompactFlash slot • Expansion slot in PDA for memory capabilities • USB port for easy PC interfacing HP iPAQ2215 Figure 3: http://www.circuitcity.com/detail.jsp?c=1&b=g&u=c&qp=0&bookmark=bookmark_0&oid=74016&catoid=-8028&m=0

  17. Central Unit Technical Aspects • PDA • 64 MB internal RAM • Up to 512 MB of add-on memory • 900 mAh lithium rechargeable battery • Software must be programmed for PDA to record and store GPS data (every half hour) • Software must also be programmed to receive, store, and manipulate accelerometer data • All programming will be done using the software development kit (SDK) from Microsoft

  18. Social Design Specifications • Laipac Global Positioning System (GPS) • Tracking GPS compact flash card (to log distance and location) • Low power consumption • Windows compatible Figure 4: http://www.laipac.com/gps_tf30cf_eng.htm

  19. Social Technical Aspects • GPS • Record readings every half hour • Accurate to 25 m • 3.3 V • .2 W power consumption • PDA driver is downloadable from the website

  20. Thank you! • We just want to extend our thanks to: • Dr. Montgomery • Prof. Justin Williams • Dr. Jim Abbs • Daryn Belden • Gary Diny, PT

  21. Future Work • The plan for the device is thoroughly mapped out. The next steps include: • Purchasing the PDA and CompactFlash card • Writing the software with the SDK for the GPS • Purchasing the pieces for the accelerometer • Purchasing the circuit board and assembling the system • Design and build casing for the accelerometers • Write software using the SDK for the accelerometer • Test the integrated system

  22. Overall schematic Reference Accelerometer Integrated PDA and GPS Upload data to PC Accelerometer Figure 5: www.circuitcity.com

  23. References • Davis, William R. Personal Interview. 14 Feb. 2004. • Department of Neurology. (2001). What are Movement Disorders and How are they Treated? Retrieved March 8, 2004, from Baylor College of Medicine Web site: http://www.bcm.tmc.edu/neurol/struct/park/park6.html • Diny, Gary. Personal Interview. 27 Feb. 2004. • Hobson, J.P., et al., eds. “The Parkinson’s Disease Activities of Daily Living Scale: a new simple and brief subjective measure of disability in Parkinson’s disease.” Clinical Rehabilitation 15:1 (2001): 241-246. • Meyers, Allan R., et al., eds. “Health-Related Quality of Life in Neurology.” Neurology and Public Health 57:1 (2000): 1224-1227. • Montgomery, Erwin B. Personal Interview. 27 Jan. 2004. • Deep Brain Stimulation surgery. Retrieved April 25, 2004. http://www.clevelandclinic.org/neuroscience/techniques/dbs.htm • Deep Brain Stimulation Surgery. Retrieved April 25, 2004. www.wemove.org

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