Surface Concentration of Antimicrobial Function

1. Surface Concentration of Antimicrobial Function Kenneth J. Wynne, Virginia Commonwealth University, DMR 0207560 Polymer Surface Modifier A A B B P[AB] = Bulk polyurethane • Fluorous side chain A surface-concentrates biocidal C-12 alkylammonium B (n = 0.11) • Only 2wt% P[AB] polyurethane modifier effects complete kill in 30 min of aerosol spray of E. coli, S. aureus, and P. aeruginosa • Potential applications: catheters, gloves Complete kill on 2wt% modified polyurethane Control 464 colonies P. aeruginosa • Collaborative, interdisciplinary research: Grad student, Pinar Kurt (CLSE); Drs. D. Ohman, Lynn Wood, VCU School of Medicine, Department of Microbiology and Immunology • Kurt, P.; Wood, L.; Ohman, D. E.; Wynne, K. J., Langmuir; (Letter); 23(9); 4719-4723, 2007.

2. Functional Polymer Surfaces Kenneth J. Wynne, Virginia Commonwealth University, DMR 0207560 • Outreach: • Collaborative international training for graduate students from Kyoto Univ. (Prof. Chujo) and Univ. of Pisa (Prof. Chiellini and Prof. Galli). • Collaborative international training in surface science for undergrads from Koç Univ. (Prof. Yilgor) • Panel member, May 07, NSF STC “Center on Materials and Devices for Information Technology Research”, University of Washington, Seattle • Co-Organizer, K-12 Workshop / Symposium “Polymer Science of Everyday Things”, Boston ACS, August 07. • Education: • Two Ph.D.’s: Dr. Janelle Uilk (Phillip Morris) and Dr. Umit Makal (Novion) • One post-doctoral: Professor Tomoko Fujiwara (U. Memphis) • REU undergrads 06: Ms. R. Wickham (Grad School U. Md, Fall 07). • Three Ph.D. graduate students are being trained: Ms. Pinar Kurt (4th yr), Ms. Allison Mullins (3rd yr and Mr. Kennard Brunson (2nd yr). • Grad course development: Polymers in Medicine