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Screening of some Iranian plants to find bioactive compounds

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Screening of some Iranian plants to find bioactive compounds

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    2. Screening of some Iranian plants to find bioactive compounds K. Javidnia, R. Miri, H. Rezai, A. Jafari, A. Azarmehr, F. Talebi, N. Faham and Z. Amirghofran Medicinal & Natural Products Chemistry Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz university of Medical Sciences Shiraz, Iran Central Research of Natural Resource and Animal Husbandry, Yasuje, Iran Department of Immunology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    9. K-562 cell line (IC50=1.29) A5 (IC50 = 14.0) Jurkat (IC50 = 22.6)

    12. 5-methoxy podophylotoxin

    13. 5-methoxy podophylotoxin

    17. Plant. Dracocephalum kotschyi Boiss. Immunosuppresive activity Bioactive fractionation guided Methanol extract was partitioned between Hexane Ethylacetate LTT test N-Butanol Final (H2O)

    24. Calycopterin

    25. Dose-dependent suppression of calycopterin (?) on mitogen-induced lymphocyte proliferation. Dexamethasone (¦) was used as positive control. Data represented the mean ± SE of three individual experiments.

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