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Stats 11, Winter 2004

Stats 11, Winter 2004. Experimental Design Jan 9, 2004. London Cholera Outbreak, 1854. Cholera kills quickly Primary symptom is severe diarrhea • Modern treatment involves an IV to provide hydration • Competing Theories for transmission: air vs water (germs). Air was the predominant view.

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Stats 11, Winter 2004

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  1. Stats 11, Winter 2004 Experimental Design Jan 9, 2004

  2. London Cholera Outbreak, 1854 • Cholera kills quickly • Primary symptom is severe diarrhea • Modern treatment involves an IV to provide hydration • Competing Theories for transmission: air vs water (germs). Air was the predominant view.

  3. Golden Square, Sept 1854 • Unusually intense, deadly outbreak • 500 deaths in just a few days • Local panic made neighbors flee • John Snow, a physician, believed cholera spread through polluted water supplies

  4. Is this definitive "proof"?

  5. Same picture, but with daily deaths

  6. Aside: quarterly aggregates

  7. Fiscal Year aggregates

  8. Calendar Year aggregate

  9. Water compnies

  10. This area was fed by two water companies

  11. Deathrate less where clean water

  12. Current medical mystery • Sudan's Luckless Children, Locked in Land of Nod, NY Times, Sept 22, 2003 • Mysterious ailment among some children of Sudan • Nod, don't grow fully, die in late teens • Theories: fly bite, poison, contaminated food

  13. References found on • http://www.ph.ucla.edu/epi/snow.html

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