1 / 37

HPV Rollout Training

HPV Rollout Training. Session 2: HPV Testing Protocol. HPV Triage. To detect women with low grade cytology who may have underlying high grade abnormality. HR-HPV Negative. cytology likely to regress without treatment Some cases of high grade CIN will be HR-HPV negative.

ryu
Download Presentation

HPV Rollout Training

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. HPV Rollout Training Session 2: HPV Testing Protocol

  2. HPV Triage To detect women with low grade cytology who may have underlying high grade abnormality

  3. HR-HPV Negative • cytology likely to regress without treatment • Some cases of high grade CIN will be HR-HPV negative Borderline: High risk HPV negative

  4. HR – HPV Negative Avoid anxiety of repeat screening tests NPV is 93.8-99.7%

  5. HR- HPV Positive Some will have no cervical abnormality Some will have low grade CIN Some will have high grade CIN More later…

  6. Test of Cure Women who have had treatment for CIN To assess their risk of having residual or recurrent disease Avoid need for unnecessary repeat samples

  7. HPV Testing Protocol

  8. ???

  9. HPV Triage

  10. HPV Triage

  11. HPV Triage (outcome 1)

  12. HPV Triage (outcome 2)

  13. HPV Triage (outcome 3)

  14. HPV Triage (summary)

  15. HPV Positive Samples • Women referred to colposcopy • Number of possible outcomes:

  16. At colp (outcome 1)

  17. At colp (outcome 2)

  18. At colp (outcome 3)

  19. Outcome at colp (summary)

  20. Test of Cure (TOC)

  21. Test of Cure (TOC) • Women treated for CIN • Only if proven CIN on LLETZ/Cone • Cytology must be neg/BC/Mild • If cytology high grade then colposcopy • Not done if previous invasive cancer or CGIN/ endocervical adenocarcinoma

  22. HPV Test Of Cure

  23. TOC • If HPV test unavailable/unsatisfactory? • Repeat sample in 3 months

  24. Negative at TOC

  25. Positive at TOC

  26. HPV triage & TOC • Should reduce dramatically the time spent on diagnosis and treatment • More about the results later…

  27. Implementation • Increased demands on colposcopy services in the initial stages • Programme funding over years 1 and 2 is structured to reflect the specific plan • Cost-savings should be realised from year 3

  28. Year One • Triage • Conducted on only the first occurrence of BC/Mild cytology (routine invitation) • TOC • Restricted to newly treated women whose follow up cytology is neg/BC/mild

  29. Year Two • Triage • Extend to all BC and mild samples • TOC • Extend to all women treated for CIN who have neg/bc/mild cytology

  30. Straightforward at first Can get complicated later on! Follow protocol, if in doubt do what is best in your clinical opinion, do least harm HPV Testing protocol

  31. Or do what I do sometimes … • Ask Karin!

  32. Any Questions?

More Related