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Genetic Diseases. Genetic Diseases. Genetic Diseases can result from many things such as mutations in the gene or mutations in chromsome number First lets recall a view facts…. A female will have an two ____ chromosomes A male will have an ___ and ___ chromosom
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Genetic Diseases • Genetic Diseases can result from many things such as mutations in the gene or mutations in chromsome number • First lets recall a view facts…. • A female will have an two ____ chromosomes • A male will have an ___ and ___ chromosom • Also some diseases can be either __________ or sex-linked related
Down Syndrome • Also known as Trisomy 21 • There is an extra 21st chromosome • This disease is an example of nondisjunction • Nondisjucntion - where the chromsomes fail to ________ during meiosis • Polyploidy -
Short in stature • Will develop many health problems • Mental Retardation
Turner Syndrome • Occurs in ________, they lack an X chromsome, so they are XO • Females will be short in stature, infertile, have a webbed neck, and low ears
Klienfelter’s Syndrome • Occurs in ________ • They will be infertile • Tall, and possibly Mentally impaired
Pedigree’s • Scientist used to study the inheritance patterns in a family and the possible offspring • Can be used to predict the possibility of disease
Genetic Engineering “Dad, can you pass the genetically modified corn please?”
Genetic Engineering • Can used in various ways – to create transgenic animals, to help with medicines, in forensics (crime solving), in crop production • Transgenic Organisms – contain genes from other ___________
Chickens engineered To have no feathers • Better poultry for the farmers
Also transgenic plants • Plants and crops will be more resistant to harsh weather • Resistant to diseases • Resistant to insecticides
Cloning • Making an exact copy – genetically • Will take DNA from the organism and place the DNA in an egg cell from another donor
Dolly the sheep was The first successful Animal cloned
Ethical Issues • Genetic Engineering raises many ethical concerns. • Ethical meaning right vs. wrong • Think about what makes genetic engineering ethical or unethical. • Write a paragraph about your position
Other Applications • PCR – Polymerase Chain Reaction – making more DNA from small amounts – amplifying the DNA • Inserting human DNA into bacteria cells • Gene Therapy – replaces defective genes with normal genes