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Lower Urinary Tract Symptoms (LUTS) in men. Kamal Patel GPST2. Objectives. Define ‘LUTS’ Causes of LUTS Initial assessment and management Not covered Mx of acute retention Stress incontinence Prostate Ca.
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Lower Urinary Tract Symptoms (LUTS) in men Kamal Patel GPST2
Objectives • Define ‘LUTS’ • Causes of LUTS • Initial assessment and management • Not covered • Mx of acute retention • Stress incontinence • Prostate Ca
A 79 year-old man complains of LUTS. Which one of the following regarding BPH is incorrect? • Goserelin is licensed for refractory cases • Side effects of 5α-reductase inhibitors include ejaculation disorders and gynaecomastia • Possible presentation include recurrent UTI • 5α-reductase inhibitors typically decrease the PSA • More common in black men.
LUTS: definition • Storage (irritative) symptoms: • Urgency • Urinary frequency • Nocturia • Urinary incontinence • Voiding (obstructive) symptoms • Hesitancy, poor stream, terminal dribbling
Causes of LUTS • Obstructive • BPH • Prostate/bladder/rectal cancer • Bladder neck/urethral strictures • Antimuscarinic drugs • Autonomic neuropathy/neurogenic bladder
Causes of LUTS • Irritative • BPH • Bladder/prostate cancer • Infection • Bladder stones • Neurological • Dementia • Diabetes • Stroke
Assessment • History – type of LUTS, duration of Sx, how bothersome are they? • Examination – abdomen (distended bladder), external genitalia, DRE • International Prostate Symptom Score: • Used to assess severity of symptoms • Score of 0-5 for seven symptoms (total 35): • 0-7 – mildly symptomatic • 8-19 – moderately symptomatic • 20-35 – severely symptomatic
A 62 year-old man presents with nocturia, hesitancy and terminal dribbling. DRE reveals a moderately enlarged prostate with no irregular features. PSA1.3 What is the most appropriate mx? • Alpha antagonist • 5-alpha reductase inhibitor • Non-urgent referral for TURP • Empirical tx with cipro for 2 weeks • Urgent referral to urology.
A patient is started on finasteride for the management of BPH. How long should the patients be told that treatment may take to be effective? • Within 8hrs of taking the tablet • Within 3 days • Up to 7 days • Up to 4 weeks • Up to 6 months
Management • Urine dip +/- culture • U&E • Chronic retention • Recurrent UTI • Hx of renal stones • PSA • Urinary frequency-volume chart • Ask patient to note down when they drink fluid/pass water and to comment on type of fluid • Allows to differentiate between frequency of urine, polyuria and nocturia
Obstructive symptoms • Lifestyle changes. • Alpha blocker: e.g tamsulosin • 5α – reductase inhibitors • Irritative symptoms • Exclude/manage treatable causes • Urine containment devices • Supervised bladder retraining • Anticholinergics e.g oxybutinin