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Blood Types. Objective: Determine how blood types are inherited and how co-dominance applies to the ABO system. Genetics of Blood. Your blood type is established before you are born, by specific genes inherited from your parents. These two genes - one gene from your mother
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Blood Types Objective: Determine how blood types are inherited and how co-dominance applies to the ABO system
Genetics of Blood • Your blood type is established before you are • born, by specific genes inherited from your • parents. • These two genes - one gene from your mother • and one from your father - determine your • blood type.
Who Has What Type? source: http://www.bloodbook.com/type-facts.html
Genotypes & Phenotypes • There are 4 different types of blood: • A, B, AB & O. • Blood types (phenotypes) are determined by the following allele or gene combination (genotype): • Give the genotype(s) for each blood type. • Type A = ____ ____ Type AB = ____ • Type B = ____ ____ Type O = ____ AB AO AA BO OO BB
Dominant & Recessive • O is recessive • A is dominant • B is dominant • What happens if A + B?
Co-dominance A B Since A & B are both dominant it is co-dominant AB A new blood type results…AB
Example: Dad has Type B blood type (phenotype) because he has a B gene (blue) and an O gene (yellow) genotype. B O A B A O A Mom has Type A blood because she has an A gene (red) and an O gene (yellow) B O O O O
Example: Dad has Type B blood type (phenotype) because he has a B gene (blue) and an O gene (yellow) genotype. B O A O A A B ? Type A phenotype Mom has Type A blood because she has an A gene (red) and an O gene (yellow) B O O O O Type O phenotype Type B phenotype
Exercise 1: Dad has Type A blood (phenotype) because he has a A gene (red) and an O gene (yellow) A O O Mom has Type O blood (phenotype) because she has an O gene (yellow) and an O gene (yellow) genotype. O
Answer Key 1: Dad has Type A blood (phenotype) because he has a A gene (red) and an O gene (yellow) A O O O A O O Type A phenotype Type O phenotype Mom has Type O blood (phenotype) because she has an O gene (yellow) and an O gene (yellow) genotype. O A O O O Type O phenotype Type A phenotype
Exercise 2: Dad has Type A blood (phenotype) because he has a A gene (red) and an A gene (red) genotype A A A Mom has Type AB blood (phenotype) because she has an A gene (red) and an B gene (blue) genotype . B
Answer Key 2: Dad has Type A blood (phenotype) because he has an A gene (red) and an A gene (red) genotype A A A A A A A Type A phenotype Type A phenotype Mom has Type AB blood (phenotype) because she has an A gene (red) and an B gene (blue) genotype . A B A B B Type AB phenotype Type AB phenotype
Dad has Type B blood (phenotype) because he has a B gene (blue) and an B gene (blue) genotype Exercise 3: Mom has Type B blood (phenotype) because she has an B gene (blue) and an O gene (yellow) genotype
Dad has Type B blood (phenotype) because he has a B gene (blue) and an B gene (blue) genotype Answer Key 3: B B B B B B B Type B phenotype Type B phenotype Mom has Type B blood (phenotype) because she has an B gene (blue) and an O gene (yellow) genotype B O O B O Type B phenotype Type B phenotype
Dad has Type AB blood (phenotype) because he has an A gene (red) and a B gene (blue) genotype Exercise 4: Mom has Type A blood (phenotype) because she has an A gene (red) and an O gene (yellow)
Answer Key 4: Dad has Type AB blood (phenotype) because he has an A gene (red) and a B gene (blue) genotype B A A A B A A Mom has Type A blood (phenotype) because she has an A gene (red) and an O gene (yellow) Type AB phenotype Type A phenotype B O O A O Type B phenotype Type A phenotype
Dad has Type B blood (phenotype) because he has a B gene (blue) and an O gene (yellow) genotype Bonus Exercise: Mom has Type A blood (phenotype) because she has an A gene (red) and an O gene (yellow) genotype.
Dad has Type B blood (phenotype) because he has a B gene (blue) and an O gene (yellow) genotype Bonus Answer Key: B O B A A O A Mom has Type A blood (phenotype) because she has an A gene (red) and an O gene (yellow) genotype. Type AB phenotype Type A phenotype O B O O O Type B phenotype Type O phenotype
Optional Extension • Ask your parents if they know their blood type. • Ask your parents if they know your blood type.