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Jheng -Fong Jhong ( 鍾政峰 ) , Yung Chang ( 張雍 ),

雙離子性氟素材於傷口癒合之應用開發. Jheng -Fong Jhong ( 鍾政峰 ) , Yung Chang ( 張雍 ), . 2012/11 /20. R&D Center for Membrane Technology and Department of Chemical Engineering, Chung Yuan University, Taiwan ( 中原大學薄膜技術研發中心 ). 雙離子性氟素材於傷口癒合之應用開發. General concept of wound healing. 雙離子性氟素材於傷口癒合之應用開發.

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Jheng -Fong Jhong ( 鍾政峰 ) , Yung Chang ( 張雍 ),

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  1. 雙離子性氟素材於傷口癒合之應用開發 Jheng-Fong Jhong(鍾政峰), Yung Chang (張雍), 2012/11/20 R&D Center for Membrane Technology and Department of Chemical Engineering, Chung Yuan University, Taiwan (中原大學薄膜技術研發中心)

  2. 雙離子性氟素材於傷口癒合之應用開發 General concept of wound healing

  3. 雙離子性氟素材於傷口癒合之應用開發 Membranes used in human body • The performance of designed surfaces contact with human blood? General Surface Designed Surface Hemocompatible Control

  4. 雙離子性氟素材於傷口癒合之應用開發 General synthetic systems Cell membrane polyether Widely used: “Ideal anti-fouling candidates Bio-mimetic “Nature bioinert surface” Oligo(ethylene glycol) (OEG)-based materials Sulfobetaine methacrylate (SBMA) Poly(ethylene glycol) (PEG)-based materials

  5. Plasma treatment Atmospheric Pressure Plasma Jet (APPJ) Flow rate: 10 slm Ar Argon March box Plasma jet Sample 150W < > < > RF power generator Characterization Input power: 150 W • Without vacuum system • Time reduction • Low energy consumption X-Y axis controller

  6. 雙離子性氟素材於傷口癒合之應用開發 Plasma induced surface modification Ar+ F F F

  7. 雙離子性氟素材於傷口癒合之應用開發 Plasma induced surface modification - - - - + + + + Biomimetic Interface

  8. 雙離子性氟素材於傷口癒合之應用開發 Animal wound healing test 2.5cm 2.5cm 1.5cm 1cm 1cm SDrat 1.5cm Age 8~10 week (420g) wound

  9. 雙離子性氟素材於傷口癒合之應用開發 Platelet RBC Bacterial

  10. 雙離子性氟素材於傷口癒合之應用開發

  11. Acknowledgement • We wish to express their sincere gratitude to • The Center-of-Excellence (COE) Program on Membrane Technology from the Ministry of Education (MOE), R.O.C. • The National Science Council for their financial support. CENTER for MEMBRANE T ECHNOLOGY RESEARCH & DEVELOPMENT

  12. THANK YOU FOR YOUR ATTENTION

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