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Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix. Osteoscoop - Issue N°101 - October 2009. Wnt. LRP5/6. Wnt. Extracellular. Sclerostin. Krm. LRP5/6. Dkk. Cytoplasm. β-catenin. β-catenin. Lysosomes. TCF. TCF. Nucleus. Nucleus. Wnt. Osterix.
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Inhibition of Wnt signalingby the osteoblast-specific transcription factor Osterix Osteoscoop - Issue N°101 - October 2009
Wnt LRP5/6 Wnt Extracellular Sclerostin Krm LRP5/6 Dkk Cytoplasm β-catenin β-catenin Lysosomes TCF TCF Nucleus Nucleus
Wnt Osterix LRP5/6 Wnt Extracellular Sclerostin Krm LRP5/6 Dkk Cytoplasm β-catenin β-catenin Lysosomes TCF TCF Nucleus Nucleus
Wnt Osterix LRP5/6 Wnt Extracellular Sclerostin Krm LRP5/6 Dkk Cytoplasm β-catenin β-catenin Lysosomes TCF Osterix TCF Nucleus Nucleus