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Endocrine System. Endocrine System. Endocrine glands are composed of cells that secrete: Hormones amino acid derivatives peptides and proteins steroids . Hormones act by attaching to receptors of specific target cells. Function of endocrine system: homeostasis
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Endocrine System • Endocrine glands are composed of cells that secrete: • Hormones • amino acid derivatives • peptides and proteins • steroids
Hormones act by attaching to receptors of specific target cells
Function of endocrine system: • homeostasis • growth and development
Endocrine Glands • Hypothalamus • oxytocin production • ADH production • production and secretion of regulatory hormones for anterior pituitary
Pituitary (hypophysis) • posterior pituitary • oxytocin secretion • ADH secretion
Pituitary (hypophysis) • anterior pituitary • Tropic hormones • TSH • ACTH • Gonadotropins: FSH, LH • Prolactin • Growth hormone
all anterior pituitary hormones are regulated by hypothalamic hormones • regulation dependent upon hypophyseal portal system
Thyroid Gland • T4 and T3: released by thyroid follicles • calcitonin: released by C cells
Parathyroid glands • PTH
Adrenal cortex • mineralocorticoids • glucocorticoids • adrenal androgens • Adrenal medulla • E and NE
Endocrine pancreas • Islets of Langerhans • glucagon: from alpha cells • insulin: from beta cells • somatostatin: from delta cells
Pineal gland • melatonin • Heart • ANP • Kidney • renin • EPO
Thymus Gland • thymosin
Reproductive System • Testes • testosterone • inhibin • Ovaries • estrogens • progesterone
Endocrine Disorders • Acromegaly
Endocrine Disorders, continued • Acromegaly • Gigantism
Endocrine Disorders, continued • Acromegaly • Gigantism • Pituitary Dwarfism
Endocrine Disorders, continued • Goiter
Endocrine Disorders, continued • Goiter
Endocrine Disorders • Grave’s disease
Endocrine Disorders, continued • Cretinism
Endocrine Disorders, continued • Cushing’s disease
Endocrine Disorders, continued • Cushing’s disease • Addisons disease
Endocrine Disorders, continued • Type I diabetes • Type II diabetes