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Viruses are the greatest threat to humans, and the current pandemic shows how these pathogens can shut down the country, stop the entire industry, and cause endless suffering to humans as they spread through communities.
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Huateng Pharma https://en.huatengsci.com/ What Are Viruses And What Kills Viruses in the Body? Viruses are the greatest threat to humans, and the current pandemic shows how these pathogens can shut down the country, stop the entire industry, and cause endless suffering to humans as they spread through communities. What Are Viruses? Viruses are very tiny, even much smaller than cells. Its structure is very simple, consisting only of a gene strand (DNA or RNA or both) and protein coat. In some ways, viruses are both living and non-living. They have genetic information that evolves through natural selection. They assemble themselves. But they don't have any kind of internal chemical processes for sustaining life, such as growing, reproducing, or adapting to their environment. They can only reproduce by hijacking a host cell and using its machinery to make more viruses. Image modified from Wikimedia, CC BY-SA 2.5 Diseases such as SARS, measles, hepatitis, yellow fever, Ebola, AIDS, influenza, and smallpox as we all know are all caused by viruses. Viruses are
Huateng Pharma divided into RNA viruses and DNA viruses. Measles virus, SARS virus, Ebola virus, and influenza virus are all RNA viruses; while smallpox virus and bacteriophages are DNA viruses. For viruses, such special organisms, we must not only defend against their harm but also understand them in a deeper level. Viruses use the metabolic capacity of cells to achieve reproduction. When they are not lodged in cells, they are more like non-living bodies. After the virus is transmitted into the body, it only takes a few simple steps to cause harm. First, The virus recognizes and binds to a host cell via a receptor molecule on the cell surface and enters the cell. Then, the virus uses the host cell to replicate proteins and nucleic acids and make the virus capsid. The third step is to release the assembled viral nucleic acid and outer capsid from the ruptured cell to infect new cells. This kind of invasion and copying is extremely fast, and 100,000 copies can be produced within six hours. https://en.huatengsci.com/ What Kills Viruses in the Body? The virus selection of hosts will be limited. The receptor-binding protein on their capsid, like a "key", invades the cell by "unlocking" the cell wall of the host. Generally, a key can only open a lock, but the mutation of the virus can transform the key and suddenly open the "lock" of cells of other species. Therefore, the virus carried by animals breaks through the species boundary and infects people.
Huateng Pharma https://en.huatengsci.com/ Our bodies are constantly fighting against invading organisms (including viruses). Our first line of defense is skin, mucus and stomach acid. If we breathe in the virus, the mucus will trap and try to expel it. If swallowed, stomach acid may kill it. If the virus crosses the first line of defense, the innate immune system will work. Phagocytes wage war and release interferons to protect surrounding cells. If phagocytes cannot destroy their invasive power, they will call lymphocytes into play. Our lymphocytes, T cells and B cells, retain the memory of any previous infections that are severe enough to put them in battle. Antibodies are formed, and the body knows how to fight any infections it recognizes. (This is how vaccination works. The human body has fought similar infections). But viruses can mutate, sometimes so much that their bodies cannot recognize them as similar infections they have fought in the past. They also act so fast that they can kill the lymphocytes before they do. Compared with RNA viruses, DNA viruses are more stable. The process of DNA virus reproduction is not prone to mutations. Therefore, after the immune system remembers the characteristics of the DNA virus in the vaccine, it can easily recognize and eliminate the virus for a long time. However, RNA viruses are different. They will have many mismatches and recombinations during their reproduction, constantly changing their characteristics. Therefore, vaccine
Huateng Pharma development for RNA viruses is more difficult. COVID-19 is a more variable RNA virus, so its vaccine development is even more difficult. https://en.huatengsci.com/ In the face of the raging virus, people hope to develop a class of chemical substances that directly kill the virus. But until now, no medications have ever been developed to kill the virus itself. Antibiotics will not kill the virus. They kill bacteria, not viruses. They kill the good bacteria that we need to keep intestinal balance. Taking antibiotics during viral infections may cause Candida to overgrow immediately, thereby providing the immune system with additional system-wide infections to deal with when it needs all of its resources to fight a viral infection. Antiviral medications do not directly kill the virus, they just inhibit a specific process of virus activity, such as trap it within the cell, keeping it from reproducing. For example, oseltamivir (a specific inhibitor of neuraminidase), its mechanism of action is to prevent the virus from exiting the host cell. Ribavirin (anti-retroviral drug), its mechanism of action is to prevent virus nucleic acid replication, thereby controlling the reproduction of the virus. How does oseltamivir work Don't panic. Most viruses don't affect us. But still, it brings up a point. Viral infections are a symptom of a weak immune system. A healthy nutrient dense diet, a healthy lifestyle, and a body void of as many toxins as possible is the first and foremost defense. Also, with the rapid development of molecular biotechnology, biochemistry, genetics and immunology, new types of vaccines such as subunit vaccines, recombinant vaccines, and nucleic acid vaccines for different infectious and
Huateng Pharma non-infectious diseases are constantly coming out. We have eliminated smallpox, effectively blocked the spread of polio, and are gradually conquering HIV and curing hepatitis C. So, we should believe that we will definitely develop a vaccine for COVID-19. https://en.huatengsci.com/ Huateng Pharma, a professional pharmaceutical company with a 34000m² industrial park, has large scale manufacturing capabilities at our modern facility. We supply PEG derivatives and anti-cancer & anti-virus APIs and intermediates to customers worldwide. Our capabilities include rapid initial scale-up and custom synthesis of intermediates with the capacity to produce up to tons.