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Endocrine System. Endocrine System Disorders. Hyposecretion : under production Treated with drug therapy Hypersecretion : over production Treated with surgery Common cause: genetic defect. Cretinism. Hypothyroidism in infants
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Endocrine System Disorders • Hyposecretion: under production • Treated with drug therapy • Hypersecretion: over production • Treated with surgery • Common cause: genetic defect
Cretinism • Hypothyroidism in infants • Mental retardation, impaired growth, low body temperatures, abnormal bone formation
Myxedema • Hypothyroidism in adults • Edema, low blood levels, weight gain, cold intolerance, fatigue, depression, muscle or joint pain, sluggishness
Graves Disease • Hyperthyroidism • Elevated metabolic rate, abnormal wt loss, excessive perspiration, weakness and emotional instability • exopthalmos- protruding eyes • Goiter- enlarged goiter
Addison Disease • Deficiency of cortical hormones • Muscle weakness, anorexia, gastrointestinal symptoms, fatigue, hypoglycemia, hypotension, hyponatremia, and hyperkalemia
Cushing Syndrome • Excessive amounts of cortisol and ACTH in the blood • Wt gain, moon-shaped face, exaggerated head and trunk, thin arms and legs • Hirsutism: excessive hair growth in unusual places
Type I Diabetes • Diagnosed children and young adults • Body does not produce sufficient insulin • Treatment includes injection of insulin
Type 2 Diabetes • Onset later in life • Risk factors: family hx, diabetes and obesity • Body is deficient in producing sufficient insulin • Body is resistant to insulin action in target cells
Type 2 Diabetes • Hyperglycemia: cell starvation, damage kidneys, eyes, nerves or heart • Tx: exercise, diet, wt loss, medication
Diabetic Ketoacidosis (DKA) • Caused: too little insulin, failure to follow a prescribed diet, physical or emotional stress or undiagnosed diabetes
Gestational Diabetes • Diabetes develops during pregnancy • Inability to metabolize carbohydrates • Resolves after childbirth • Increase risk for developing Type 2 Diabetes
Acromegaly • Chronic metabolic disorder characterized by a gradual, marked enlargement and thickening of the bones and the face and jaw
Diuresis • Increased formation and secretion of urine
Glucosuria • Presence of glucose in the urine or abnormal amount of sugar in the urine
Hyper’s & Hypo’s • Hypercalcemia • Hyperkalemia • Hypervolemia • Hyponatremia
Thyroid Storm • Crisis of uncontrolled hyperthyroidism caused by the release into the bloodstream of increased amount of thyroid hormone
Virile • Masculine or having characteristics of a man
Virilism • Masculinization in a woman or development of male secondary sex characteristics in the women
Exopthalmometry • Test that measures the degree of forward displacement of the eyeball
Fasting Blood Glucose • Test that measures blood glucose levels after a 12-hour fast
Glucose Tolerance Test (GTT) • Test that measures the body’s ability to metabolize carbohydrates by administering a standard dose of glucose and measuring glucose levels in the blood and urine at regular intervals
Insulin Tolerance Test • Test that determines insulin levels in serum by administering insulin and measuring blood glucose levels in blood at regular intervals
Thyroid Function Test (TFT) • Test that detects an increase or decrease in thyroid function
Thyroid Scan • After injection of a radioactive substance, a scanner detects radioactivity and visualizes the thyroid gland
Microneurosurgery of the pituitary gland • Microdissection of a tumor using a binocular surgical microscope for magnification
Parathyroidectomy • Excision of one or more of the parathyroid glands, usually to control hyperparathyroidism
Thymectomy • Excision of the thymus gland
Thyroidectomy • Excision of the thyroid gland • Partial- method of choice for removing a fibrous nodular thyroid • Subtotal- removal of most of the thyroid to relieve hyperthyroidism