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Water Balance, Thermoregulation, Fight or Flight, Male and Female Reproductive. Overview of Regulation (Blood-Glucose tomorrow). Cell Interaction with Target Cells. Amino and Peptide Hormones Bind to receptors on the outside of the cell (cell specific)
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Water Balance, Thermoregulation, Fight or Flight, Male and Female Reproductive Overview of Regulation (Blood-Glucose tomorrow)
Cell Interaction with Target Cells • Amino and Peptide Hormones • Bind to receptors on the outside of the cell (cell specific) • Are not lipid soluble, therefore can not pass through the membrane • cAMP (cyclic andenosinemonophosphate) – cell messenger • Activate enzymes that produce the needed hormone Ex: TSH attaches to the receptor sites of the thyroid gland, cAMP results and produces enzymes to produce hormone
Lipid/Steroid Hormones • Enter cells by crossing the membrane (lipid soluble) • Bind to receptors on nuclear membrane • Hormone-receptor complex binds to DNA • Activation of genes that produce enzymes required for hormone production
Water Balance Osmotic Pressure – concentration of ‘stuff’ in the blood (Ca, Na) ADH – antidiuretic hormone Promotes absorption of water in kidneys • Nerve cells in hypothalamus detect concentrated blood; send water to the blood; shrink in size • ADH sent to kidneys to reabsorb water; sends water to blood • As blood becomes dilute, ADH is no longer released. Hypothalamus: Nerve Anterior Pituitary: ADH Kidney: Increase water reabsorption
Kidney Disease • Can’t process body wastes effectively • Kidney stones • Dialysis • Exchange of substance • Diffusion of blood
Thermoregulation T3thyroxine T4triiodothyronine • Which target all cells of body • Increase metabolic rate • Glucose Energy Heat http://dwb.unl.edu/teacher/nsf/c01/c01links/www.science.mcmaster.ca/biology/4s03/thermoregulation.html
Fight or Flight/Stress • Adrenal glands - on top of kidneys • Produces: Epinephrine and Norepinephrine • Causes fight of flight response • Blood glucose level rises • Metabolic rate increases • Bronchioles dilate • Breathing rate increases • Blood vessels to digestive tract and skin constrict; those to skeletal muscles dilate • Cardiac muscle contracts more forcefully and heart rate increases • Also produces cortisol • Breaks down of muscle protein to amino acids • Breaks down fatty acids • Raises blood glucose levels. • Counteracts inflammatory response
Female Reproductive • Hypothalamus • GnRH • Anterior Pituitary • LH • FSH • Ovary • Growing Folicle (FSH & LH) • Estrogen – Feedback (need more) – Ovulation • Corpus Luteum (LH) • Progesterone – Feedback (inhibits)
Male Reproductive • Hypothalamus • GnRH • Anterior Pituitary • LH • FSH • Testes • Sertoli Cells (FSH) • Influence sperm production • Inhibition (feedback) • Interstitial Cells (LH) • Testosterone – Feedback (need more) – Sent to sertoli cells
Interests/Hobbies/Sports • Animals/Farming • Outdoors • Music • Farming • Gymnastics • Horseback riding • Soccer • Tug-of-war