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Trapped allele

Supplementary Figure 1. frt. F3. frt. F3. lx5171. lxP. lxP. lx5171. E1. OPE. OPE. OPE. OPE. OPE. OPE. E2. pA. SA. b geo. pA. inversion at F3 sites. inversion at frt sites. E1. E2. pA. OPE. OPE. OPE. OPE. OPE. OPE. SA. b geo. pA. Inversion by FLP. E1. OPE. OPE.

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Trapped allele

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  1. Supplementary Figure 1 frt F3 frt F3 lx5171 lxP lxP lx5171 E1 OPE OPE OPE OPE OPE OPE E2 pA SA bgeo pA inversion at F3 sites inversion at frt sites E1 E2 pA OPE OPE OPE OPE OPE OPE SA bgeo pA Inversion by FLP E1 OPE OPE OPE OPE OPE OPE E2 pA pA bgeo SA excision at frt sites excision at F3 sites E1 pA bgeo SA E2 pA inversion at lxP sites inversion at lx5171 sites SA bgeo pA E1 E2 pA Re-inversion by Cre SA bgeo pA E1 E2 pA SA bgeo pA E1 E2 pA excision at lx5171 sites excision at lxP sites Trapped allele Inverted allele Re-inverted allele

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