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Blood. Components of Blood. Whole blood RBCs WBCs Platelets: cell fragments that aid in clotting Plasma 90% water (allows materials to dissolve) Amino acids, glucose, hormones, vitamins, salts, waste Concentrations allows diffusion in/out of blood stream. Click picture to play.
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Components of Blood • Whole blood • RBCs • WBCs • Platelets: cell fragments that aid in clotting • Plasma • 90% water (allows materials to dissolve) • Amino acids, glucose, hormones, vitamins, salts, waste • Concentrations allows diffusion in/out of blood stream
Red Blood Cells • Produced from stem cells in bone marrow • Lose nucleus as they mature • Transport O2 to cells; remove CO2 • O2 binds to hemoglobin proteins • Dead cells filtered by liver & spleen
Sickle Cell Normal
ABO Blood Groups • Proteins on blood cells determine blood type • Antigen • proteins on cells that identify cells as foreign or natural • on the surface of RBCs • Antibodies: • proteins from WBCs to attack invaders • in the blood plasma
Group A blood • A antigens on the surface of your RBCs • B antibodies in your blood plasma
Group B blood • B antigens on the surface of your RBCs • A antibodies in your blood plasma
Group AB blood • A and B antigens on the surface of your RBCs • no A or B antibodies at all in your blood plasma
Group O blood • No A or B antigens on the surface of your RBCs • both A and B antibodies in your blood plasma
Rh Factors • Rh+ • Protein found in blood • Can receive Rh+ or Rh- blood • Rh- • Lack protein in blood • Only receive Rh- blood
Francis was just in a bad accident and lost a lot of blood. He is blood type B+. Can you help save him?
Blood type B+ Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh
B+ B antigens Rh antigens B+ B antigens Rh antigens B+ B antigens Rh antigens This person has B+ blood type because of the B and Rh antigensCan he accept B+ blood? Yes. The A antibodies do not have A antigens to attack. Therefore, no attacking and clumping of blood cells will occur. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
B- B antigens B- B antigens B- B antigens This person has B+ blood type because of the B and Rh antigensCan he accept B- blood? Yes. The A antibodies do not have A antigens to attack. Therefore, no attacking and clumping of blood cells will occur. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
A+ A antigens Rh antigens A+ A antigens Rh antigens A+ A antigens Rh antigens This person has B+ blood type because of the B and Rh antigensCan he accept A+ blood? No. The A antibodies will attack the A antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
A- A antigens A- A antigens A- A antigens This person has B+ blood type because of the B and Rh antigensCan he accept A- blood? No. The A antibodies will attack the A antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
AB+ A antigens B antigens Rh antigens AB+ A antigens B antigens Rh antigens AB+ A antigens B antigens Rh antigens This person has B+ blood type because of the B and Rh antigensCan he accept AB+ blood? No. The A antibodies will attack the A antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
AB- A antigens B antigens AB- A antigens B antigens AB- A antigens B antigens This person has B+ blood type because of the B and Rh antigensCan he accept AB- blood? No. The A antibodies will attack the A antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
O+ Rh antigens O+ Rh antigens O+ Rh antigens This person has B+ blood type because of the B and Rh antigensCan he accept O+ blood? Yes. The A antibodies do not have A antigens to attack. Therefore, no attacking and clumping of blood cells will occur. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
O- No antigens O- No antigens O- No antigens This person has B+ blood type because of the B and Rh antigensCan he accept O- blood? Yes. The A antibodies do not have A antigens to attack. Therefore, no attacking and clumping of blood cells will occur. Vein B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody B+ B antigens Rh antigens A antibody
Sebastian was just involved in an accident at work and lost a lot of blood. He is blood type A-. Can you help save him?
Blood type A- Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh
A- A antigens A- A antigens This person has A- blood type because of the A antigenCan he accept A- blood? A- A antigens Yes. The B and Rh antibodies do not have antigens to attack. Therefore, no attacking and clumping of blood cells will occur. A- A antigens Rh antibody B antibody A- A antigens A- A antigens Rh antibody B antibody
A+ A antigens Rh antigens A+ A antigens Rh antigens This person has A- blood type because of the A antigenCan he accept A+ blood? A+ A antigens Rh antigens No. The Rh antibodies will attack the Rh antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. A- A antigens Rh antibody B antibody A- A antigens A- A antigens Rh antibody B antibody
B- B antigens B- B antigens This person has A- blood type because of the A antigenCan he accept B- blood? B- B antigens No. The B antibodies will attack the B antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. A- A antigens Rh antibody B antibody A- A antigens A- A antigens Rh antibody B antibody
B+ B antigens Rh antigens B+ B antigens Rh antigens This person has A- blood type because of the A antigenCan he accept B+ blood? B+ B antigens Rh antigens No. Both B and Rh antibodies will attack the B and Rh antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. A- A antigens Rh antibody B antibody A- A antigens A- A antigens Rh antibody B antibody
AB- A antigens B antigen AB- A antigens B antigen This person has A- blood type because of the A antigenCan he accept AB- blood? AB- A antigens B antigen No. The B antibodies will attack the B antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. A- A antigens Rh antibody B antibody A- A antigens A- A antigens Rh antibody B antibody
AB+ A antigens B antigens Rh antigens AB+ A antigens B antigens Rh antigens This person has A- blood type because of the A antigenCan he accept AB+ blood? AB+ A antigens B antigens Rh antigens No. Both B and Rh antibodies will attack the B and Rh antigens. This will cause the blood cells to clump, thus stopping blood flow. This person may die. A- A antigens B antibody Rh antibody A- A antigens A- A antigens Rh antibody B antibody
O- No antigens O- No antigens This person has A- blood type because of the A antigenCan he accept O- blood? O- No antigens Yes. The antibodies do not have antigens to attack. Therefore, no attacking and clumping of blood cells will occur. A- A antigens B antibody Rh antibody A- A antigens A- A antigens Rh antibody B antibody
O+ Rh antigens O+ Rh antigens This person has A- blood type because of the A antigenCan he accept O+ blood? O+ Rh antigens Yes. The antibodies do not have antigens to attack. Therefore, no attacking and clumping of blood cells will occur. A- A antigens B antibody Rh antibody A- A antigens A- A antigens Rh antibody B antibody
Blood type AB+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type O+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type AB- Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type B+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type O- Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
White Blood Cells • Remove foreign invaders & dead cells • Able to move through body tissue
Platelets • Form clots when bleeding • Proteins form a web to trap cells & platelets