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HEART TRANSPLANTATION

HEART TRANSPLANTATION. Pediatric Recipients. ISHLT. 2012. J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS. ISHLT. 2012. J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095.

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HEART TRANSPLANTATION

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  1. HEART TRANSPLANTATION Pediatric Recipients ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  2. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  3. AVERAGE CENTER VOLUME AND PERCENTAGE OF TRANSPLANTS BY CENTER VOLUMEPediatric Heart Transplants: January 1, 2000 - June 30, 2011 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  4. PEDIATRIC HEART TRANSPLANTS Distribution of Transplants By Location and Average Center Volume (Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  5. DISTRIBUTION OF TRANSPLANTS By Center VolumePediatric Heart Transplants: January 1, 2000 - June 30, 2011 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  6. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS(Transplants: January 2000 - June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  7. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTSBy Year of Transplant NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of hearts transplanted worldwide has increased and/or decreased in recent years. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  8. PEDIATRIC HEART TRANSPLANTSAge Distribution By Location (Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  9. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS (Transplants: January 2000 - June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  10. PEDIATRIC HEART TRANSPLANTSDonor Age Distribution By Location (Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  11. DISTRIBUTION OF TRANSPLANTS by Donor/Recipient Weight Ratio(Pediatric Heart Transplants: January 1, 2000 - June 30, 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  12. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: < 1 Year) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  13. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 1-10 Years) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  14. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 11-17 Years) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  15. PEDIATRIC HEART TRANSPLANTSDiagnosis Distribution By Location (Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  16. PEDIATRIC HEART RECIPIENTS% of Patients Bridged with Mechanical Circulatory Support* by Year (Transplants: January 2005 – December 2010) ISHLT 2012 * LVAD, RVAD, TAH, ECMO J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  17. PEDIATRIC HEART RECIPIENTS% of Patients Bridged with Mechanical Circulatory Support* (Transplants: July 2004 – June 2011) ISHLT 2012 * LVAD, RVAD, TAH, ECMO J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  18. PEDIATRIC HEART RECIPIENTS% of Patients Bridged with Mechanical Circulatory Support* by Age Group (Transplants: July 2004 – June 2011) ISHLT 2012 * LVAD, RVAD, TAH, ECMO J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  19. PEDIATRIC HEART RECIPIENTSPRA Distribution by Year (Transplants: 2005 – 2010) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  20. PEDIATRIC HEART RECIPIENTSPRA Distribution by Age Group (Transplants: July 2004 – June 2011) ISHLT p-value = 0.0001 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  21. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival (Transplants: 1/1982-6/2010) 0-<1 vs. 1-10: p = 0.0041 0-<1 vs. 11-17: p = 0.9859 1-10 vs. 11-17: p = 0.0003 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  22. PEDIATRIC HEART TRANSPLANTSConditional Kaplan-Meier Survival (Transplants: 1/1982-6/2010) 0-<1 vs. 1-10: p = 0.0003 0-<1 vs. 11-17: p < 0.0001 1-10 vs. 11-17: p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  23. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: 1/1982-6/2010) All p-values significant at p = 0.001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  24. PEDIATRIC HEART TRANSPLANTSConditional Kaplan-Meier Survival for Recent Era(Transplants: 1/2000-6/2010) 0-<1 vs. 1-10: p = 0.0272 0-<1 vs. 11-17: p = 0.0008 1-10 vs. 11-17: p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  25. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: 1/1982-6/2010)Age: < 1 Year 1982-1989 vs. 1990-1999: p = 0.0057 1982-1989 vs. 2000-6/2010: p < 0.0001 1990-1999 vs. 2000-6/2010: p < 0.0001 Half-life 1982-1989: 10.8 years; 1990-1999: 18.3 years; 2000-6/2010: n.c. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  26. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: 1/1982-6/2010)Age: 1-10 Years All p-values significant at p = 0.0001 Half-life 1982-1989: 8.0; 1990-1999: 14.3; 2000-6/2010: n.c. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  27. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: 1/1982-6/2010)Age: 11-17 Years 1982-1989 vs. 1990-1999: p = 0.0158 1982-1989 vs. 2000-6/2010: p < 0.0001 1990-1999 vs. 2000-6/2010: p = 0.0311 Half-life 1982-1989: 9.3; 1990-1999: 11.4; 2000-6/2010: n.c. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  28. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis (Transplants: 2000-6/2010)Age: < 1 Year p-value < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  29. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis (Transplants: 2000-6/2010)Age: 1 - 10 Years Congenital vs. Cardiomyopathy: p < 0.0001 Congenital vs. Retransplant: p = 0.0154 Cardiomyopathy vs. Retransplant: p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  30. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis (Transplants: 2000-6/2010)Age: 11 - 17 Years Congenital vs. Cardiomyopathy: p = 0.0526 Congenital vs. Retransplant: p = 0.1841 Cardiomyopathy vs. Retransplant: p=0.0024 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  31. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Patient vs. Graft Survival (Transplants: 1/2000-6/2010)Average Center Volume: 1-4 Transplants per Year p = 0.1973 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  32. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Patient vs. Graft Survival (Transplants: 1/2000-6/2010)Average Center Volume: 5-9 Transplants per Year p = 0.0580 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  33. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Patient vs. Graft Survival (Transplants: 1/2000-6/2010)Average Center Volume: 10+ Transplants per Year p = 0.0135 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  34. PEDIATRIC HEART RECIPIENTS Cross-Sectional Analysis Functional Status of Surviving Recipients (Follow-ups: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  35. PEDIATRIC HEART RECIPIENTS Functional Status of Surviving Recipients (Follow-ups: January 2000 – June 2011)Age: <1 Year ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  36. PEDIATRIC HEART RECIPIENTS Functional Status of Surviving Recipients (Follow-ups: January 2000 – June 2011)Age: 1-10 Years ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  37. PEDIATRIC HEART RECIPIENTS Functional Status of Surviving Recipients (Follow-ups: January 2000 – June 2011)Age: 11-17 Years ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  38. PEDIATRIC HEART RECIPIENTSFunctional Status of Surviving Recipients US Recipients Only(Follow-ups: March 2005 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  39. PEDIATRIC HEART RECIPIENTSRehospitalization Post-transplant of Surviving Recipients (Follow-ups: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  40. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression(Transplants: January 2001 – June 2011) ISHLT Analysis is limited to patients who were alive at the time of the discharge 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  41. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression(Transplants: January 2001 – June 30, 2011) Test of increasing trend over time: Any induction p < 0.0001 Polyclonal p < 0.0001 IL-2R p < 0.0001 ISHLT 2012 Analysis is limited to patients who were alive at the time of the discharge J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  42. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Induction Group Conditional on Survival to 14 Days (Transplants: January 2000 – June 2010) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  43. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Induction Group and Treated Rejection Between Transplant Discharge and 1-Year Follow-up (1-Year Follow-ups: July 2004 - June 2010) Conditional on Survival to 1 Year Treated rejection = Recipient was reported to (1) have at least one acute rejection episode that was treated with an anti-rejection agent; or (2) have been hospitalized for rejection. No rejection = Recipient had (i) no acute rejection episodes and (ii) was reported either as not hospitalized for rejection or did not receive anti-rejection agents. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  44. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Induction Group Conditional on Survival to 14 Days (Transplants: January 2000 – June 2010)Age: <1 Year ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  45. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Induction Group Conditional on Survival to 14 Days (Transplants: January 2000 – June 2010)Age: 1-10 Years ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  46. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival by Induction Group Conditional on Survival to 14 Days (Transplants: January 2000 – June 2010)Age: 11-17 Years ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  47. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-up(Follow-ups: January 2001 – June 2011) ISHLT Analysis is limited to patients who were alive at the time of the follow-up 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  48. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-upfor Same Patients at Each Time Point(Follow-ups: January 2001 – June 2011) ISHLT Analysis is limited to patients who were alive at the time of the follow-up 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  49. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-up (Follow-ups: January 2001 – June 2011) NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT Analysis is limited to patients who were alive at the time of the follow-up 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  50. PEDIATRIC HEART TRANSPLANTSKaplan-Meier Survival Based on Prednisone UseConditional on Survival to 1 Year (Transplants: January 2000 - June 2010) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

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