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Patient Survival

Patient Survival. USA Primary DD Pancreas Transplants 1/1/2004 – 12/31/2008. Category n 1Yr Surv. PTA 491 96.4% PAK 1,136 96.6% SPK 4,206 95.2%. 2/09. Major Causes of Patient Death. USA Primary DD Pancreas Transplants 1/1/2004 – 12/31/2008. %. SPK. PAK. PTA.

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Patient Survival

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  1. Patient Survival USA Primary DD Pancreas Transplants 1/1/2004 – 12/31/2008 Category n 1Yr Surv. PTA 491 96.4% PAK 1,136 96.6% SPK 4,206 95.2% 2/09

  2. Major Causes of Patient Death USA Primary DD Pancreas Transplants 1/1/2004 – 12/31/2008 % SPK PAK PTA 0-3 3-12 > 12 0-3 3-12 > 12 0-3 3-12 > 12 Months Posttransplant 3/09

  3. 1-Year Patient Survival USA Primary DD Pancreas Transplants 1/1/2004 – 12/31/2008 3/08

  4. Higher Risk Lower Risk Factors for Patient Survival USA DD Primary Pancreas Transplants, 1/1/2004 – 12/31/2008

  5. Pancreas Graft Function USA DD Primary Pancreas Transplants 1/1/2005 – 12/31/2009 Cat. n 1Yr Fxn SPK 4,146 85% PAK 947 79% PTA 465 78% p < 0.0001 3/10

  6. Pancreas Graft Function USA DD Primary Pancreas Transplants 1/1/2004 – 12/31/2008 DWFx Pancreas censored Cat. n 1Yr Fxn PAK 1,136 81.0% PTA 491 81.0% SPK 4,200 88.2% p < 0.0001 3/09

  7. Major Causes of Px Graft Failure USA Primary DD Pancreas Transplants 1/1/2004 – 12/31/2008 % SPK PAK PTA 0-<3 3-<12 ≥ 12 0-<3 3-<12 ≥ 12 0-<3 3-<12 ≥12 Months Posttransplant 3/09

  8. 1-Year Pancreas Graft Function USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2007 4/06

  9. Higher Risk Lower Hazard Ratio for Pancreas Graft Loss USA DD Primary Pancreas Transplants, 1/1/2000 – 12/31/2005 PTA SPK PAK Donor Age

  10. Higher Risk Lower Hazard Ratio for Pancreas Graft Loss USA DD Primary Pancreas Transplants, 1/1/2000 – 12/31/2007

  11. 1-Year Pancreas Graft Function USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2006 4/08

  12. 1-Year Pancreas Graft Function USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2006 4/06

  13. Higher Risk Lower Hazard Ratio for Pancreas Graft Loss USA DD Primary Pancreas Transplants, 1/1/2000 – 12/31/2005 SPK PAK PTA Preservation Time [hrs]

  14. Technical Failure Rate USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2005 P = 0.0001 Donor Cause of Death

  15. Graft Thrombosis Rate USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2005 P = 0.0001 Donor Cause of Death

  16. Higher Risk Lower Hazard Ratio for Technical Failure USA DD Primary Pancreas Transplants, 1/1/2000 – 12/31/2005 SPK PAK PTA Donor Age

  17. Higher Risk Lower Hazard Ratio for Graft Thrombosis USA DD Primary Pancreas Transplants, 1/1/2000 – 12/31/2005 SPK PAK PTA Donor Age

  18. Higher Risk Lower Hazard Ratio for Graft Thrombosis USA DD Primary Pancreas Transplants, 1/1/2000 – 12/31/2005

  19. Immunological Pancreas Graft Loss USA Primary TS DD Pancreas Transplants 1/1/2004 – 12/31/2008 Cat. n 1Yr Loss PTA 445 6.0% PAK 1,016 5.5% SPK 3,879 2.1% p = 0.0001 3/09

  20. Even the Highest Risk Patients Do Better with a SPK than Remaining on the Waiting List UNOS Pancreas Waiting List 1/1/1995– 5/31/2003 University of Minnesota SPK Recipients 2/04

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