Human Genome Sciences Large Scale Manufacturing Facility

1. Human Genome Sciences Large Scale Manufacturing Facility Aaron Trout Construction Management Senior Thesis Presentation

2. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Building Information • Function: Pharmaceutical Manufacturing Facility • Location: Rockville, MD • Cost: $233,400,000 • Size: 290,000 ft2 • Schedule: April 4,2003 – July 2005 Project Players • Owner: Human Genome Sciences, Inc. • Architect/Engineer: Lockwood Greene Engineers • CM: Gilbane Building Company Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

3. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Analysis 1 - 4D Modeling Purpose of Analysis? • Assist with coordination of equipment delivery • Show work flow of specific interior finishes and exterior wall system • Identify potential conflicts in the field Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

4. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions What is 4D Modeling? • A 4D model is created by combining a 3D model with the appropriate scheduling data, hence adding the aspect of time. Advantages of 4D Models • Improve constructability • Ability to analyze activity sequencing • Identify spatial conflicts between crews • Improve work flow for subcontractors Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

5. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Components of LSM Model • Depicts first floor only (sequence can be replicated for second floor) • Sequencing focuses on the “clean rooms” & MER room • Exterior metal wall panels & structural support • Metal Studs & Drywall • Epoxy flooring • Equipment Pads • Air Handling Units Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

6. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Sequence of Activities • Installation of steel tubing followed by wall panels • Metal studs • Drywall after building enclosure • Equipment pads after building enclosure • Epoxy flooring follows drywall and equipment pads • Air handling units delivered after epoxy has cured • Section of wall panels and equipment pads left out • Equipment pads & AHU • Epoxy floor for MER room • Steel tubing and wall panel West Elevation of LSM Facility Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

7. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions LSM 4D Model Created using Auto CAD, Microsoft Project, and Common Point Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

8. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Analysis 2 – Exterior Wall System Purpose of Analysis? • Value Engineering • Add aesthetic value to facility • Reduce cost • Reduce duration • Improve constructability Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

9. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Analysis of Exterior Wall System • 2” preformed metal wall panels as specified by architect • Two different systems were analyzed • Exterior Insulation and Finishes System • Architectural Precast Concrete Panels Metal Wall Panels by “Centria” EIFS Brick Finish Precast Structure Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

10. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Preformed Metal Wall Panels • Description • Urethane Foam Insulation • Exterior 22 gage stainless steel w/embossed pattern • 2”x8”x1/4” steel tubing @ 7ft. offset for support • Advantages • Installed easily and efficiently • Minimal maintenance required resulting in long service life • Resistant to impact and damage as well as the elements • Disadvantages • Long lead time associated with custom design • Costly to replace and install damaged panels • Buckling of panels is correct spacing is not allotted Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

11. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Exterior Insulation and Finishes System • Description • 2x4 stud framing • Plywood Substrate • 4” EPS insulation w/adhesive • Base coat w/reinforcing mesh • Acrylic finish coat Detail of EIFS System • Advantages • Continuous insulation prevents water penetration • Very light system only 4pfs • Versatile system for numerous finishes, textures, and colors • Inexpensive system • Disadvantages • No interior drainage cavity which could cause mold if not installed properly • More susceptible to damage than other systems but inexpensive to repair Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

12. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Architectural Precast Concrete Panels • Description • Manufactured in a plant then shipped to site • 2” of concrete, 2” of polystyrene insulation, 2” of concrete • 20’x10’ sections with a smooth gray finish • Advantages • No cold/hot weather issues • With proper coordination the schedule can be reduced • Quality assurance • Ability to be load bearing • Very durable • Disadvantages • Cost • Shipping panels to site • Could have long lead time for specialty shapes Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

13. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

14. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Adjusted Values • Metal Wall Panels • Duration: 14 weeks • EIFS • Duration: 25 weeks • Double Crew Size • Duration: 13 weeks • Cost: $901,425 • Precast Concrete Panels • Duration: 10 weeks * Best system for cost and duration is the EIFS System Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

15. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Calculate Heat Transfer Through Wall For metal wall panel: Heating: qx = ((70 – 8) * 35,700) / 14.5 = 152,648 Btu/h Cooling: qx = ((94 – 70) * 35,700) / 14.5 = 59,090 Btu/h For EIFS: Heating: qx = ((70 – 8) * 35,700) / 16.83 = 131,516 Btu/h Cooling: qx = ((94 – 70) * 35,700) / 16.83 = 50,909 Btu/h Difference Between Systems Heating: 152,648 Btu/h - 131,516 Btu/h = 21,132 Btu/h Cooling: 59,090 Btu/h - 50,909 Btu/h = 8,181 Btu/h = 0.68 tons % Reduction of heating and cooling loads Heating: (21,132 Btu/h / 8,000,000 Btu/h) * 100 = 0.26% Cooling: (0.68 tons / 3,000 tons) * 100 = 0.02% * The savings in operations cost for heating and cooling is negligible Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

16. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Conclusion • The EIFS system would provide the most benefit to HGS • Increase aesthetic value • Reduce cost by $500,000 or $350,000 • Impact schedule by +11 weeks or -1 week • Though negligible increase energy efficiency Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

17. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Analysis 3 – Floor Covering Purpose of Analysis? • Value Engineering • Reduce installation time of floor covering • Improve constructability • Reduce cost Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

18. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Analysis of Floor Covering for “Clean Rooms” • Quartzite Epoxy Flooring as specified by architect • Two different systems were analyzed • Bonded Conductive Terrazzo • Conductive Epoxy Terrazzo Epo-Rok Quartz by Valspar Example of bonded terrazzo Example of epoxy terrazzo Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

19. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Quartzite Epoxy Flooring • Description • ¼” thick • Installed in 3 layers which each require 24 hours to cure • Epoxy shop coat, quartz aggregate, heavy epoxy coat • Various aggregate colors • Advantages • Seamless system • Resistant to chemicals, slip, and collection of dust • Very durable surface • Disadvantages • Takes time to install • Costly to replace and install damaged areas Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

20. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Bonded Conductive Terrazzo • Description • Average thickness is 2” thick • Consists of a cementitious binder and an aggregate • Aggregate: marble, quartz, granite or glass • Terrazzo is poured in place, allowed to cure, ground down, then polished • Advantages • Resistant to impact damage and daily wear and tear • Resistant to chemicals due to conductive nature • Disadvantages • Can be difficult and expensive to repair • Not 100% resistant to liquid • Dividers requires at control joints to prevent cracking Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

21. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Conductive Epoxy Terrazzo • Description • ¼” thick • Consists of an epoxy binder and an aggregate • Aggregate: marble, quartz, granite or glass • Epoxy primer is set, epoxy system is toweled into place, grouted to fill voids, then polished and sealed • Advantages • Similar to that of the quartzite epoxy flooring • Disadvantages • One of the most expensive systems • Can be expensive and time consuming to repair Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

22. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

23. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Conclusion • The specified quartzite epoxy system would provide the most benefit to HGS • Least expensive system • Takes least amount of time to install • No more difficult or expensive to repair than other systems • Durable, chemical resistant, slip resistant, will not collect dust Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

24. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Final Conclusions • By incorporating a 4D model to the LSM facility the CM can: • Identify spatial conflicts between crews • Analyze activity sequencing • Visually interpret work to be done in the clean & MER rooms • An EIFS system would be a positive Value Engineering decision • Increase aesthetic value • Reduce total project cost • Will not impact the schedule • Use the specified floor covering for the “clean rooms” • The quartzite epoxy system is the least expensive and takes the least amount of time to install • Characteristics of other systems are not superior Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

25. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Acknowledgements The Architectural Engineering Dept. Dr. John Messner Dr. Michael Horman Dr. David Riley Human Genome Sciences Raj Vora, PE Joe Morin Gilbane Building Company Andy Faber Chuck Brawley Ted Trester Mike Curry Tim McNeal Mark Rummel Lola Poe Taylor Shannon Croissette Friends and Family My Mom and Dad My roommates Fellow peers in AE Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University

26. Human Genome Sciences Large Scale Manufacturing Facility Introduction 4D Modeling Description Model of LSM Facility Exterior Wall System Description of systems Cost and Schedule Impact Heat Transfer Conclusion Floor Covering Description of systems Cost and Schedule Impact Conclusion Closing Statements Questions Questions? Aaron Trout Senior Thesis 2005 Construction Management The Pennsylvania State University