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Criteria for Selection and Responsibilities of Regional Leading Laboratory

Criteria for Selection and Responsibilities of Regional Leading Laboratory Samia Metwally, DVM, PhD (FAO) Gregorio Torres (OIE). Lab Network- One Tool of the Global Strategy.

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Criteria for Selection and Responsibilities of Regional Leading Laboratory

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  1. Criteria for Selection and Responsibilities of Regional Leading Laboratory Samia Metwally, DVM, PhD (FAO) Gregorio Torres (OIE)

  2. Lab Network- One Tool of the Global Strategy • Develop, maintain and strengthen an integrated international, regional and national network of laboratories that can respond quickly to needs for rapid and accurate testing, and timely notification • Gain more intelligence on FMD virus strains circulating in regions • Improve vaccine selection – supporting both endemic and free countries and essential to progressive control • Enhance diagnostic capability for other priority diseases in the region

  3. FMD Lab and Epidemiology Networks Diagnostic analysis Surveillance, monitoring, and disease tracking

  4. OIE-FAO FMD Ref Lab NetworkFMD Seven Regional Virus Pools 3 1 2 4 5 7 6 WRL- FMD Reference lab/centers

  5. Current Status of FMD ReferenceLab Network • OIE/FAO FMD reference lab network • One world and twelve reference labs/centers • Annual meeting, training and work plans • Provide diagnostic services • Share disease status information in respective regions • Create a comprehensive FMD report on an annual basis

  6. Diagnostics Requirements for PCP Stages 1 2 3 4 5 Identify risk and control options Implement risk-based control Implement Control strategy to eliminate circulation Maintain zero circulation and incursions Surv & early detection Maintain zero circulation; withdraw vaccination Quality Ctr & Assurance VI, characterization, molecular dx, vaccine matching (Biocontainment) Monitoring Typing and SP ELISA VP1 sequencing Screening ELISA /PCR In country Region/reference

  7. Surveillance Approaches

  8. Regional Leading LaboratorySelection Criteria • Creditability and acceptance by countries of the region • Commitment from the government to support and sustain lab functions as described in the terms of reference • Lab capacity and capability to perform diagnostics for FMD/PPR/other TADs • Capability to handle exotic viruses from other countries in the region • Certification to ship and receive international diagnostic samples • Participated or willingness to take part in OIE twinning program • Keen interest to be designated as a FAO/OIE reference center • Established link with FMD reference laboratorty • Maintain good performance on proficiency testing carried by reference center

  9. Regional Leading LaboratoryTerms of Reference • Produces diagnostic reagents, SOPs and protocols • Provides training to national laboratories using train the trainers approach • Coordinates proficiency testing for the region (limited to screening tests) • Receives and processes samples for diagnostics from countries of the region • Ships samples to FAO/OIE reference centers for full characterization • Ensures and assist in regional procurement of essential diagnostic reagents for emergency release • Participates in regional laboratory network activities (potential leader) • Links with the regional epidemiology network

  10. Regional Leading LaboratoryProcedures for Nomination • Acceptance by countries of the region • Meeting the selection criteria • Government official commitment to support terms of reference/responsibilities

  11. Thank you for your attention

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