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Muscle Metabolism

Muscle Metabolism. Aerobic respiration: produces large amounts of ATP but requires O 2 to function, waste products: water, CO 2 Anaerobic fermentation: produces small amounts of ATP in absence of O 2 waste product: lactic acid (major factor in fatigue). Muscle Metabolism.

wynter-clemons
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Muscle Metabolism

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  1. Muscle Metabolism • Aerobic respiration: produces large amounts of ATP but requires O2 to function, waste products: water, CO2 • Anaerobic fermentation: produces small amounts of ATP in absence of O2 waste product: lactic acid (major factor in fatigue)

  2. Muscle Metabolism • There are three phases to muscle metabolism • Each is designed to give muscle tissue energy during strenuous activities

  3. Muscle Metabolism • Immediate energy: during intense exercise oxygen is quickly depleted in muscle(6sec) so ATP is made by grabbing Pi from donor molecules and adding it to ADP to make ATP • Donor molecule: Creatine kinase grabs a Pi from creatine phosphate (CP) and adds to ADP to make ATP, nearly all ATP during short burst are produced this way (phosphagen system)

  4. Muscle Metabolism • Short term energy: once the phosphagen system is depleted the body goes into anaerobic respiration. It can generate energy for 40 sec in intense activity • Long term energy: after 40 sec the body cardiovascular system catches up and is able to deliver the needed oxygen to the muscles for aerobic respiration

  5. Fatigue • Fatigue: the gradual weakness and loss of contractility • ATP production decreases as glucose is used up • Low levels of ATP slows Na/K pumps • Lactic acid inhibits ATP production • K+ in the ECF makes cell less excitable • ACh becomes depleted

  6. Oxygen Debt • Oxygen Debt: occurs after exercise. Due to the following • Oxygen reserves: oxygen is dissolved in tissues in the body that are depleted first and need to be replaced • Phosphagen system: ATP must be made, then broken to give Pi back to creatine • Oxidizing lactic acid: most of lactic acid will be converted into glucose in the presence of oxygen • Metabolic rate: if body temp is high the metabolic rate is high and requires oxygen to break down molecules

  7. Muscle Fibers • Slow oxidative (SO): Red fibers with lots of mitochondria and blood capillaries better for aerobic activity • Fast glycolytic (FG): White fibers with large storage of phosphagen and lactic systems better for quick responses but not endurance

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