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T-Cell Receptor Signaling

LAT. B7-2. CaCn. B7-1. MHC-II. TRIM. P A G. Ag. GRB2. GADS. CD4/CD8. C D 4 5. SLP76. CD28. ZAP70. Lck. PKC . SIT. CTLA4. SOS. SHP2. SHP2. PI3K. Caln. VHR. MEK1/2. CARD11. Fyb. PLC g. P. I k B. BCL10. MAP3Ks. Fyn. Fyn. PAK. Calm. ITK. JNK. CSK. Akt. p38.

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T-Cell Receptor Signaling

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  1. LAT B7-2 CaCn B7-1 MHC-II TRIM PAG Ag GRB2 GADS CD4/CD8 CD45 SLP76 CD28 ZAP70 Lck PKC SIT CTLA4 SOS SHP2 SHP2 PI3K Caln VHR MEK1/2 CARD11 Fyb PLCg P IkB BCL10 MAP3Ks Fyn Fyn PAK Calm ITK JNK CSK Akt p38 Raf1 IKKs P P P P P P P P P P ERK1/2 IP3R MEKK1 MKK3/6 IkBDegradation SRF MKK4/7 MALT1 NF-kB NF-kB NFAT NFAT NFAT CTLA4 CTLA4 2009 ProteinLounge.com Vav ATF2 c-Jun Rac Ca2+ Ca2+ Ca2+ Ca2+ Ca2+ Ca2+ Elk1 Text Text Ras Antigen-Presenting Cell CaCn PIP2 DAG TCR-CD3Complex T-Cell Receptor Signaling Cell Proliferationand Differentiation CDC42 Active Release andTranslocation of CTLA4 to Membrane IP3 CytoskeletalRemodelling CTLA4 Endosome ImmuneResponse C IL-2 GeneExpression

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