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Prokaryote vs. Eukaryote. Prokaryote vs. Eukaryote. 1 st division. Life. Prokaryotes. Eukaryotes. Bacteria. Archea. Protist. Fungi. Plants. Animals. Prokaryotes (bacteria and archea) Lack a true nucleus Keep DNA in nucleoids No membrane bound organelles Many are anaerobic
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Prokaryote vs. Eukaryote • 1st division Life Prokaryotes Eukaryotes Bacteria Archea Protist Fungi Plants Animals
Prokaryotes (bacteria and archea) Lack a true nucleus Keep DNA in nucleoids No membrane bound organelles Many are anaerobic Do not require O2 Unicellular Prokaryotes
Eukaryotes (protists, plants, fungi, animals) Presence of a nucleus Presence of membrane bound organelles For example Mitochondria to give energy Most are aerobic Require O2 for cellular respiration Most are pluricellular Eukaryotes
Prokaryotes Lack a true nucleus No membrane bound organelles Many are anerobic Unicellular Eukaryotes Presence of a nucleus Has membrane bound organelles Most are aerobic Mostly pluricellular Summary chart
But where do viruses fit in? • Debate over whether viruses are “alive” • A) Non-living arguments 1. Cannot live independently (require a host or remain dormant) 2. Not Cellular • B) Living arguments 1. Contain genetic material (RNA and DNA) 2. Reproduce
Classifying viruses • Classification based on 1. Capsids • Protein coat that surrounds the genetic material of a virus • Spherical • Cylindrical • Crystalline
Classifying viruses • 2. Diseases they cause • Viruses that affect humans are divided into 21 groups based on the differences in their genome and replication methods
Going viral(how viruses replicate) • Virus replication (No cellular division) • 1. The Lytic cycle • Kills host cell • Process • Virus binds to host (attachment) • Injects the genetic material into the host cell (entry) • The host replicates the viral genetic material (replication) • New viral particles are assembled (assembly) • The host cell breaks (lysis) and releases new viral particles (release)
1. Attachment 2. Entry 3. Replication 4. Assembly 5.a) Lysis 5. b) Release The lytic cycle
Virus replication • 2. the Lysogenic cycle • As the viral RNA becomes part of the cells chromosomes, the onset of disease can be postponed until the virus goes into its lytic cycle • Process • Attachment • Entry • Viral DNA becomes part of the host cell’s chromosomes (provirus formation)
Attachment Entry Provirus Formation The lysogenic cycle
Viral disease • Cyclical symptoms can be explained via the replication method of a virus • E.g cold sores • Appear during the lytic cycle • Disappear during the lysogenic replication cycle
Virus working for us • Virus use in biotechnology • ability to direct the activity of the hosts cell DNA • Addition of a specific gene into the virus • Virus can deliver and force organism to replicate that gene
Prions • Prions • Protein • Do not contain RNA or DNA (not a virus) • Becomes harmful when it changes its molecular shape • Cause several deadly brain diseases • Creutzfeld-Jakob disease • Mad-cow disease in bovine