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Other Blood Groups. Kidd. 1. Chromosome 18 2. Transmembrane Protein 3.Different beeween Jk a,b Jka 280 Aspartic acid Jkb 280 Aspargin 4. Find in 11 week fetus. Kidd. 1: allels Jk a / Jk b (a + b + ), (a + b - ), (a - b + ), (a - b - ) .2 : Rolling Urea carrier.
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Kidd 1. Chromosome 18 2. Transmembrane Protein 3.Different beeweenJka,b Jka280 Aspartic acid Jkb280Aspargin 4. Find in 11 week fetus
Kidd • 1: allels Jka/Jkb (a+ b+), (a+ b-), (a- b+), (a- b-) .2 : Rolling Urea carrier
Duffy • Seat on Carbohydrate • Chromosome 1 • Near the gene of Anti thrombin III & Type 1 hereditary motor and sensory neuropathy • Formation in 6-7 week fetus
Fya Fyb Fy3 Fy5 Fy6 Fyx (a+ b+) (a+ b-) (a- b+) (a- b-) Duffy
Fyx is the weak type of Fyb • Fy a,b denature with Enzyme but not for Fy 3,5
Duffy recipient of CXC (IL-8,MGSA) & CC (MCP-1) Melanoma Growth Stimulatory Activity Monocyte Chemotactic Peptide 1 • Fy a, b, 6 recipient of P.vivax, P.knovlesi
I • Chromosome 6 • N.Acetil Glucose AminilTransferase • I has 5 exons 1A, 1B, 1C, 2, 3
I • I in branching carbohydrate in Adult • i in linear carbohydrate in Child
Anti I Mycoplasma, Mlignancy • Anti i Infectious mononucleosis, Cirrhosis
