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Other Blood Groups. P. 1: Antigens P, P1, P k 2: Phenotypes P1: P, P1, P k P2: P, P k P1 k : P1, P k P2 k : P k p: -----. Antigens P k & P are on different cells. Antigen P1 is only on RBC.
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P • 1: Antigens P, P1, Pk • 2: Phenotypes P1: P, P1, Pk P2: P, Pk P1k: P1, Pk P2k: Pk p: -----
Antigens Pk & P are on different cells. • Antigen P1 is only on RBC. • Pk Ag is the precursor of P Ag. The gene of Pk is on chromosome 22. It produts Galactosil Transferase. • The gene of P is on chromosome 3.
Major Phenotypes: P1,P2 • Some of person who has P2 Ag nuturaly has Anti P1 • Anti P Biphasic Donath Landstainer PCH (Paroxysmal Cold Hemoglobinuria)
Ag P recipient of B19 • Ag P,Pkrecipient of shiga toxin • Anti TJa Ab against of PP1Pk
Lutheran • Chromosome 19 • Its near the Se gene • It has 18 Ags • 8 Ags inherent from parents • 10 Ags excite in most of pepole
Lutheran • 1: Allels Lu1(Lua) / Lu2(Lub) Lu6 / Lu9 Lu8 / Lu14 Lu18(Aua) / Lu19(Aub) • 2: Inter and Intra Individual Variation • 3: Lamininrecipient