1 / 11

Akut hæmatologi (I)

38 år tidligere rask gymnastiklæerinde Igennem nogle uger træthed, tyngdefornemmelse abdomen Søger e.l. torsdag aften Fredag 10.00: hentes af e.l. Fredag 11.00: CS Fredag 14.00: AUH. Akut hæmatologi (I). Akut hæmatologi (I). Hæmatologiske kvantiteter Leukocytter: 322 mia/L

ashling
Download Presentation

Akut hæmatologi (I)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 38 år tidligere rask gymnastiklæerinde Igennem nogle uger træthed, tyngdefornemmelse abdomen Søger e.l. torsdag aften Fredag 10.00: hentes af e.l. Fredag 11.00: CS Fredag 14.00: AUH Akut hæmatologi (I)

  2. Akut hæmatologi (I) • Hæmatologiske kvantiteter • Leukocytter: 322 mia/L • Trombocytter 700 mia/L • Hgb. 7.3 mmol/L • Udstrygning: CML lignende billede Fredag 17.00 - sendes hjem på weekend (!)

  3. Akut hæmatologi (II) • 43 år tidligere rask systemrådgiver • Igennem nogle uger træthed, løs afføring, og oppustethed • Søger e.l. , der vælger at se an • Gener persisterer, e.l. foranlediger UL • Tumormasser spredt i abdomen • Henvisning til Hæmatologisk afdeing

  4. Akut hæmatologi (II) • Subileus • Urat 1.2 mmol/L, lymfocytose 17 mia./L • Burkitt lymfom/B-ALL, tumor lyse syndrom • Hydrering, allopurinol, rasburicase • Prednison • Midlertidig dialyse

  5. Akut hæmatologi (III) • 8.00 - roll call; patient on the admission ward • 8.45 - order of blood smear • 9.15 - look at blood smear • 9.30 - referred to Hem. Dept. • 9.55 - A-vitamin derivative perorally

  6. Histologi Molekylær biologi Flow cytometri Cytogenetik Leukæmidiagnostik

  7. Cytogenetik Udstrygning Biopsi Flyvefisk Molekylær biologi Diagnostisk tidsforløb Flow cytometri 0 1 2 3 4 5

  8. HLA Klasse II Akut hæmatologi (III) • 12.15 Flow cytometri • 14.15 FISH+ t(15;17)+ • 16.00 - RQ-PCR PML/RARA+

  9. Eigil Kjeldsen

  10. APL hæmorrhagi

  11. Forløb • CML - behandlet med Glivec - CR +48 • Burkitt lymfom - autotransplanteret - CR +120 • APL - ATRA + kemoterapi - CR +36

More Related