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NIH Nanomedicine Roadmap Definitions (nihroadmap.nih/nanomedicine)

NIH Nanomedicine Roadmap Definitions (http://nihroadmap.nih.gov/nanomedicine). Nanotechnology involves the creation and use of materials and devices at the level of molecules and atoms.

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NIH Nanomedicine Roadmap Definitions (nihroadmap.nih/nanomedicine)

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  1. NIH Nanomedicine Roadmap Definitions (http://nihroadmap.nih.gov/nanomedicine) • Nanotechnology involves the creation and use of materials and devices at the level of molecules and atoms. • Nanomedicine, an offshoot of nanotechnology, refers to highly specific medical intervention at the molecular scale for curing disease or repairing damaged tissues, such as bone, muscle, or nerve. A nanometer is one-billionth of a meter, too small to be seen with a conventional lab microscope. It is at this size scale – about 100 nanometers or less – that biological molecules and structures inside living cells operate.

  2. Nanomedicine • As used by the NIH Nanoscience Roadmap Working Group, nanomedicine describes the interface of biology with nanotechnology and nanoscience to understand and treat disease. • NIH has not re-classified most of its basic research portfolio as nanotechnology – only those studies that: • use nanotechnological tools and concepts to study biology; • propose to engineer biological molecules towards functions different from what they have in nature; • Manipulate biological systems by methods more precise than can be done by molecular biology or synthetic chemistry.

  3. NIH Nanomedicine Roadmap Definitions(http://nihroadmap.nih.gov/nanomedicine) • NIH Roadmap: nihroadmap.nih.gov • Nanomedicine Grants and Funding Opportunities: Dr. Richard S. Fisher, National Eye Institute, fisherR@mail.nih.gov • Dr. Thomas Aigner, National Institute on Drug Abuse, ta17r@nih.gov

  4. National Institute on Drug Abuse (NIDA) Supported Research/Areas of Interest: • Drug Design and Development: • James Talton – Nanotherapeutics- “Oral Buprenorphine Nanoparticle Formulation” • Submitted in response to: SBIR Contract Solicitation: “Nanoscience-based Design of Therapies for Substance Abuse Treatment” (N43-4-7741)

  5. Oral BuprenorphinePlasma Concentrations in Awake Rats

  6. National Institute on Drug Abuse (NIDA) Supported Research: 2. Drug Delivery: Bruce Hinds – University of Kentucky – “Gated Carbon Nanotube Membrane Transdermal Drug Delivery” 1R01DA018822-01A2  Submitted in response to: Nanoscience and Nanotechnology in Biology and Medicine (R01) – PA-03-045

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