Mutations Smith/ Macciardi

Oct 11, 2014

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Drug discovery Lynch, Gee, Piomelli. Clinical disease Kimonis. Brain function Gage. Synapse function Gall/ Lauterborn. Cell function Smith/Cahalan/Parker. Clinial trials outcomes Goldberg / Srinivasan. Virtual worlds Hayes. Mutations Smith/ Macciardi.

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Mutations Smith/ Macciardi

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Drug discovery Lynch, Gee, Piomelli Clinical disease Kimonis Brain function Gage Synapse function Gall/Lauterborn Cell function Smith/Cahalan/Parker Clinial trials outcomes Goldberg / Srinivasan Virtual worlds Hayes Mutations Smith/Macciardi iPS cells Keirsted Research Gargus For OC Kids Clinical care Donnelly

Mutations

Mutations. What is a mutation?. …any change in genetic information. Most mutations are bad, some lead to new adaptations. Really severe mutations usually result in death. 2 main types of mutations. Chromosomal Gene. Chromosomal mutations. Affect many genes. Are usually very severe.

413 views • 17 slides

Mutations

Mutations. Chapter 12-4. What are mutations?. Any change to the genetic code Gene mutations: A change in one or a few nucleotides in a gene Chromosomal Mutations: a change in the number or structure of chromosomes. What are mutations?. Gene mutations:

240 views • 7 slides

Mutations

Mutations. Types of Mutations | Effects of Mutations. Learning Objectives Identify different changes to DNA within both genes and chromosomes Evaluate effects of changes to DNA on proteins produced and organisms’ overall survival. Mutations.

560 views • 20 slides

Mutations

Mutations. What happens when we change DNA?. Mutations. What do you think a mutation is? What happens to you during a mutation?. Mutations. Mutations are ANY change in an organism’s DNA. Mutations usually happen during if a mistake is made during replication (S phase). Mutations.

375 views • 14 slides

Mutations

Mutations. Mutations. 1. Changes in DNA sequences that affect genetic information are known as. replications. transformations. translations. mutations. Mutations. 2. The word mutation comes from the Latin word mutare , which means. duplication replication to change the effect.

624 views • 23 slides

Mutations (p. 307)

Mutations (p. 307). Mutations are changes in the genetic material. Mutations may be genetic mutations or chromosomal mutations. Genetic Mutations occur in the “code” on DNA or mRNA. Mistakes in copying the DNA: Inserting the wrong nucleotide

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Mutations or "DNA out of control'

Mutations or "DNA out of control'. Mutations (p. 262) What are mutations? Mutations are changes in the DNA sequence that are inherited. Do mutations have negative, neutral or positive side effects on an organism ? Where do mutations occur? somatic (body) cells

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Mutations

Mutations. A Mutation is a change in genetic material. There are 2 types of mutations Gene mutations Produce a change in a single gene Chromosomal mutations Produce a change in a whole chromosome. Gene Mutations. Point mutation Mutations involving one or only a few nucleotides.

271 views • 11 slides

Mutations

Mutations. What is a mutation?. A mutation is a change in genetic material Two kinds of mutations: Gene mutations Chromosomal mutations. Gene Mutations. Produce changes in a single gene Point mutation – changes in one or a few nucleotides Deletion Addition Substitution.

1.13k views • 11 slides

VII) Mutations

VII) Mutations. Mutations. Any alteration in a gene from its natural state. the change may be detrimental or benign or lead to variation Point mutations a mutation at a specific base pair Gene mutation a mutation that changes the coding for amino acid. V) Mutations. Point Mutations.

312 views • 9 slides

Mutations

Mutations. Mutations. A mutations are a change in the sequence of bases in DNA or RNA Mutations are essential for evolution to occur Mutations are the ultimate source of all new genetic material within a species Most have no effect at all Some are beneficial Some are harmful.

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12-4 Mutations

12-4 Mutations. Pg. 307. A. Kinds of Mutations. 1. Mutations are changes, or mistakes, made in the genetic material. 2. Types of Mutations: Point Mutations Frameshift Mutations Silent Mutations. A. Kinds of Mutations. 3. Point Mutations involve a change in one or a few nucleotides.

411 views • 9 slides

Mutations

Mutations. What is a mutation?. Mutation – A change in the DNA that affects inherited genetic information They may be gene mutations which result from single gene changes, or chromosome mutations. Mutations may be positive, negative or neutral. Mutations drive evolution. Mutagens.

638 views • 31 slides

Mutations

Mutations. Mutations are inheritable changes in the DNA “Failure to faithfully store genetic information” Changes can be to chromosomes or genes Current focus: changes to DNA sequences. This means an alteration in a basepair or in the order of the basepairs. Mutations. Our example:

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DNA Mutations

DNA Mutations. Objectives . Contrast gene mutations with chromosomal mutations. Mutations. What is a mutation? Any change in a DNA sequence What causes mutations? errors in replication, transcription, cell division, or by external agents. Mutations in Reproductive Cells. Affects:

563 views • 19 slides

Mutations

Mutations. What Are Mutations?. Changes in the nucleotide sequence of DNA May occur in somatic cells (aren’t passed to offspring) May occur in gametes (eggs & sperm) and be passed to offspring. Are Mutations Helpful or Harmful?. Mutations happen regularly

421 views • 31 slides

Mutations

Mutations. 1. Silent Mutations. Change in nucleotide has no effect on amino acid in protein Occurs: Introns Wobble effect. Intron Mutations. Variable effects. Intron Mutations.

377 views • 19 slides

mutations

mutations. Latin for mistake Most mutations are neutral Little or no effect. 1. Mutations are changes in genetic material. Major mutations are often harmful . Genetic disorders Types of cancer. Mutations. Harmful, Helpful or Neutral?. Some mutations are beneficial

637 views • 18 slides

MUTATIONS

MUTATIONS. Changes in DNA that affect genetic information. Mutations. A change in the order of the nucleotide bases in DNA is a mutation It can change the type of proteins a cell produces. No freckles. Freckles. Gene Mutations. Point Mutations – changes in one or a few nucleotides

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DNA Mutations and Repair

DNA Mutations and Repair. Chapter 18 Part 1. Gene Mutations and Repair. Nature of mutations Causes of mutations Study of mutations DNA repair. Source of Mutations. Nuclear accidents. Chernobyl, April 26 th , 1986. Source of Mutations.

633 views • 31 slides

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Mutations Smith/ Macciardi

Mutations Smith/ Macciardi

Presentation Transcript

Mutations

Mutations

Mutations

Mutations

Mutations

Mutations (p. 307)

Mutations or &quot;DNA out of control'

Mutations

Mutations

VII) Mutations

Mutations

12-4 Mutations

Mutations

Mutations

DNA Mutations

Mutations

Mutations

mutations

MUTATIONS

DNA Mutations and Repair

Mutations or "DNA out of control'