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UNDERSTANDING FOOT AND MOUTH DISEASE INFECTION by Cleon V. Kimberling Extension Veterinarian Colorado State University. FOR AN INFECTION TO OCCUR THERE IS A CHAIN OF EVENTS. HOST. AGENT. MODE OF ESCAPE. MODE OF TRANSMISSION. MODE OF ENTRY. SUSCEPTIBLE HOST. HOSTS. CATTLE. SWINE.
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UNDERSTANDING FOOT AND MOUTH DISEASE INFECTION by Cleon V. Kimberling Extension Veterinarian Colorado State University
FOR AN INFECTION TO OCCUR THERE IS A CHAIN OF EVENTS • HOST • AGENT • MODE OF ESCAPE • MODE OF TRANSMISSION • MODE OF ENTRY • SUSCEPTIBLEHOST
HOSTS • CATTLE • SWINE • SHEEP & GOATS • ALL CLOVEN HOOFED • ANIMALS. • CAMELIDS ARE NOT HIGHLY • SUSCEPTIBLE
RESISTANT SPECIES • HORSES • MAN • FOOT AND MOUTH DISEASE • IS NOT A HUMAN HEALTH • HAZARD
AGENT (FMD VIRUS) • VIRUS • EXTREMELY SMALL • EXTREMELY HARDY • NOT KILLED BY NORMAL • PASTEURIZATION • LIVES FOR MONTHS IN • MEAT & MILK PRODUCTS
AGENT (FMD VIRUS) • RESISTANT TO MANY • COMMON DISINFECTANTS • A LOW OR HIGH PH • KILLS THE VIRUS • VINEGAR – CLOROX • LYE (NaOH)
AGENT (FMD VIRUS) • SURVIVES FOR WEEKS OR • MONTHS IN DRIED • SECRETIONS • SURVIVES LONG PERIODS • IN COOL DAMP CLIMATES
AGENT (FMD VIRUS) • HIGHLY CONTAGIOUS • IT TAKES VERY FEW • VIRUS PARTICALS TO • CAUSE AN INFECTION • A PIECE OF INFECTED • MATERIAL THE SIZE • OF A QUARTER WILL INFECT • 1,000,000 HEAD OF CATTLE
HOW DOES THE VIRUS ESCAPE FROM THE ANIMAL? • IN RUPTURED VESCICLE FLUID • EXHALED AIR • SALIVA • MILK • SEMEN • FECES • URINE
TRANSMISSION • THE VIRUS IS SHED 5-10 • BEFORE CLINICAL SIGNS • APPEAR • VACCINATED ANIMALS CAN • SHED THE ORGANISM • RECOVERED CATTLE, SHEEP • AND BUFFALO CAN BECOME • CARRIERS
FMD VIRUS SURVIVES • UP TO 3 DAYS IN MUSCLE • FOR MONTHS IN CHILLED OR • FROZEN LYMPH NODES, BONE • MARROW, VISCERA AND • RESIDUAL BLOOD CLOTS
SOME PLACES WHERE THE VIRUS HIDES OUT • SAUSAGE/HAM/BACON • 190 DAYS • DRIED SKIM MILK 2 YEARS • CURED HIDES 352 DAYS • SURVIVAL OF THE FMD • VIRUS DEPENDS ON pH, • TEMPERATURE & HUMIDITY
MODES OF TRANSMISSION • DIRECT CONTACT & • RESPIRATORY AEROSOLS • LIVE ANIMAL MOVEMENT • ARTIFICIAL BREEDING • WINDBORNE SPREAD • PIG EMIT 1,000,000,000 I U /DAY
TRANSMISSION • ANIMAL PRODUCTS & • BY-PRODUCTS • VECTORS • MECHANICAL SPREAD/FOMITES
MODE OF ENTRY • INGESTION • INHALATION • ARTIFICIAL INSEMENATION
SUSCEPTIBILITY OF A NEW HOST • PIGS, CATTLE, SHEEP, GOATS • AND WILD ANIMALS
WHERE DO WE BREAK THE CHAIN? • PREVENT ENTRY OF THE VIRUS • ALTER THE SUSCEPTIBILITY • OF THE HOST BY VACCINATION
DISEASES THAT CAUSE BLISTERS AND SIMILAR SIGNS • VESICULAR STOMATITIS
IF YOU HAVE AN ANIMAL WITH MOUTH, FEET OR TEAT LESIONS CALL YOUR VETERINARIAN
HOW DO WE HANDLE A SUSPECTED CASE? • IMMEDIATE PREMISE • AND 1 MILE QUARANTINE
HOW DO WE DEAL WITH A FMD OUTBREAK? • QUARANTINE AND CULLING • OF ANIMALS • VACCINATION AND CULLING
WHO IS IN CHARGE? • WHO PAYS THE BILL? • WHAT ARE THE IMPACTS?
WHERE DO I GET ADDITIONAL INFORMATION? www.footandmouth.colostate.edu www.maff.gov.uk/animalh/diseases/fmd/default.html www.guardian.co.uk/gallery/0,2759,180825,00.html