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Supplemental Figure 3. Splenectomy reduces CKD-sepsis severity
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Supplemental Figure 3. Splenectomy reduces CKD-sepsis severity CD-1 mice were subjected to 5/6 Nx, and after 4 weeks subjected to splenectomy (day 0, black, dark gray bars). Three days after splenectomy (d3) sham surgery (white, black bars) or CLP (light, dark gray bars) was performed, then Scr (A), BUN (B), ALT (C), AST (D), TNFa (E), IL-6 (F), and IL-10 (G) were measured at 18 h. *P<0.05 vs 5/6 Nx-CLP