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Human Anatomy and Physiology Lab Genetic Inheritance. Anatomical Terminology and Orientation Review. Always refer to anatomical position with directions!!. Planes. Removes the top of the head? Divides the toes from the body?. Body landmarks. Brachial. Pateller.
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Anatomical Terminology and Orientation Review Always refer to anatomical position with directions!!
Planes • Removes the top of the head? • Divides the toes from the body?
Body landmarks Brachial Pateller
DNA Inherited genetic material inside each cell Composed of nucleotides 3 parts to a nucleotide: 1. Nitrogenous base -A – T -G -- C 2. Pentose sugar 3. Phosphate group - “backbone”
DNA in the Cell Located within the cell’s nucleus Remains loosely coiled in nondividing cells but forms into chromosome before dividing
Passing on DNA • Cells divide to pass on genetic material • Somatic (body) cells undergo mitosis and cytokinesis • Replaces dead or injured cells • Adds new cells during growth • Germ cells (sperm or oocytes) undergo meiosis • Produces gametes
The Cell Cycle Mitosis: Cell duplicates its contents and divides in two 3 Main Stages Interphase Mitosis Cytokinesis
Interphase • DNA replicated • Cell does most of its growing • 3 Phases: G1 - replication of most organelles and cytosolic components S – DNA replication G2– enzymes and other proteins are synthesized in prep for division
Mitotic Phase • Prophase • DNA shortens into chromosomes • Each centrosome moves to an opposite pole of cell • Nucleolus disappears, nuclear envelope dissolves • Spindle fibers and asters become visible
Mitotic Phase • Metaphase • Centromeres of chromatid pairs are aligned at exact center • Anaphase • Centromeres split, indentical sets of chromosomes moved to opposite poles
Mitotic Phase • Telophase • Chromosomes uncoil and revert to chromatin form • Nuclear envelope forms around each mass
Cytokinesis • Division of the cytoplasm • NOT A PART OF MITOSIS!! • Mitosis is a nuclear event, cytokinesis is cytoplasmic
Genotype Phenotype • AA, Ab • aa
Heterozygous female with freckles x heterozygous male with freckles 1 : 2 : 1
Incomplete Dominance Neither trait is dominant Heterozygotes show a blending of the traits
X – linked traits • Traits passed on by the sex chromosomes
Epistasis Action or expression of a gene influences that of another
Next Week • Quiz first 15-20 minutes of class. Do not be late!!! • Covers material from Labs 1 & 2 and definitions from Lab 3.
What is due today? • Integrate: Heredity: Principles of Inheritance • Objectives on page 31 • Skip questions on “sex-influenced” and “holandric” (questions # 10 & 14) • Read and answer Activity Questions on pages 33- 40, 42, and 45-46 (only do section V) • General questions # 1 - 3