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Hemophilia

Hemophilia. By: Jake Brock, & Andres Navejas. History. First text of disease was in second century AD. Jewish exempt 3 rd boy born in family from being circumcised if 2 of his older brothers died in a circumcision. Known as royal disease because Queen Victoria passed it on to her daughters

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Hemophilia

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  1. Hemophilia By: Jake Brock, & Andres Navejas

  2. History • First text of disease was in second century AD. • Jewish exempt 3rd boy born in family from being circumcised if 2 of his older brothers died in a circumcision. • Known as royal disease because Queen Victoria passed it on to her daughters • In that time royalty would marry with other royalty often being in same family.

  3. What is it? • Hemophilia is a disease in which your blood does not clot normally. • Symptoms may include bleeding a lot in small cases, bleeding into joints is common, and internal bleeding could occur too. • People can be expected to live normal lives, although a small percentage of people with disease will die from severe bleeding. • Will be detected after a abnormal bleeding episode.

  4. More what is it • There are two types • Type A • Makes up 85% of people with disease • People lack blood clotting protein called VIII • Type B • Makes up 15% of people with disease • People lack blood clotting protein called XI

  5. How its transmitted • The defective gene is carried on the X chromosome. • Women who are carriers have a 50% chance of giving it to their children. • If the male has it in his X chromosome he will have to disease. • In rare cases a mutation could occur that would give someone hemophilia without it being in the family, but overall It is a hereditary disease.

  6. Part of body targeted • Mainly internal hemorrhaging in joints, muscles, vital organs, and especially in the brain. • Effects blood by not allowing it to properly clot, which would cause people to bleed excessively.

  7. Daily life • Your daily life will be based upon how severe your case of hemophilia is since it ranges from very mild to very bad cases. • Light cases may not even need to much attention to it but being very cautious. • Bad cases will need to replace the bad clotting factors, often at birth. • Throughout the life they may need to stay on or take medications such as antifibrinolytic agents, fibrin glue, or desmopressin acetates.

  8. Resources • http://www.hemophilia-information.com/history-of-hemophilia.html • http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001564/ • http://library.thinkquest.org/05aug/00112/hemophilia_frameset.htm • Webmd.com • Wikipedia.com • Photo Sources • http://en.wikipedia.org/wiki/Red_blood_cell • http://en.wikipedia.org/wiki/File:Blood_clot_diagram.png • http://www.lyberty.com/encyc/articles/victoria.html • http://health.howstuffworks.com/human-body/systems/nervous-system/brain-pictures.htm

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