Product Overview Multi-Purpose Training System MPTS 360

Product Overview Multi-Purpose Training System MPTS 360 Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Overview • MPTS 360 • Product Description • Multi-Purpose Mask Features • MPTS 360 for Therapy • Therapy System Features • Therapy Configuration Benefits • MPTS 360 for Training • Training System Features • Training System Configuration Benefits • Product Summary Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Product Description • The Multi Purpose Training System (MPTS 360) is specifically designed to fit horses and camels. The mask kit comes with all fittings required to start training and therapy immediately. • Mask Kit • Mask with integrated mixing plenum and multi-fit seal. • Jet Nebuliser with 8mL or 20mL reservoir. Designed for superior flow delivery of therapies with Oxygen, Medical Air or Compressed Air (Pump). • Ultrasonic Vibrating Mesh Nebuliser with 8mL reservoir. Designed for quick, convenient therapy delivered at the optimum vapour size. • Robust, Variable Click Style: • Oxygen Gas Regulator. • Nitrogen Gas Regulator + Bull Nose to Pin Index Adaptor. • Safety Release Strap. • Premium Carry Case. • Instruction Manual – please read before using this Mask Kit . • Quick Start Guide Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Multi-Purpose Mask Features • Superior multi-layer mask seal designed to maintain leak-free seal despite movement and applied pressures during therapy. • Ergonomically designed mask - specifically designed to fit horses and camels. • Easy to present, fit and secure. • Low weight and excellent seal for multiple or prolonged therapies. • Integrated Plenum and Nebuliser • Compact size and reduced weight. • Robust design ensures all critical components are protected from damage. • Interchangeable delivery features for treatment and training. 1 2 3 Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Multi-Purpose Mask Features • Velcro quick release for mask and nebuliser. • The mask is designed for easy cleaning and disinfection. • The mask must be disassembled and cleaned in warm soapy water after every therapy or training session. • The mask materials can be disinfected using current veterinary disinfectants. • Easy to reassemble – Parts click into place and cannot be assembled incorrectly. 4 5 Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Multi-Purpose Mask Summary • MPTS 360 prototypes have been extensively trialled on horses and camels to ensure: • The mask is out of line of sight to help the animal remain calm during therapy. • The MPTS 360 mask offers the ultimate fit and seal on the market for horses and camels. • The MPTS 360 will withstand the rigours of therapy, training and repeated cleaning. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Therapy Delivery System Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy System Features The MTPS 360 system has been designed to allow fast, easy change-over between almost all medication delivery mediums available on the market today. Simply insert the chosen delivery system into the plenum inlet feature. Ultrasonic Nebuliser Jet Nebuliser Metered Dose Inhaler (MDI) MediVet Triple Delivery System Front View Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy System Features • The MPTS 360 is designed to optimise therapy throughout the breathing cycle by: • A low profile mask ensures CO2 rebreathing is minimised. • Vapour inhalation is prioritised and supplemented with air via the inlet vents. • Rapid air-flow is facilitated by the largest venting system of any mask currently on the market. Exhaust Vent Triple Delivery Inlet Multi-fit seal Dividing Vent Integrated Mixing Plenum Low Profile Mask Inlet Vent Section View of Mask Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy System Features The MPTS 360’s unique integrated plenum and vent system is designed to work with an animal’s natural breathing cycle to maximise therapy outcomes. Breathing Cycle Step 1: Vapour produced by the nebuliser is collected in the plenum. This prevents the nebulised vapour mixing with exhaled air and being wasted. Ground-breaking Airflow Concept Section View of Mask Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy System Features Breathing Cycle Step 2: During inhalation the nebulised vapour is drawn through the dividing vents directly into the airway. At this time, the inlet vents open to permit incoming air to complete the breath volume. Dividing Vent Inlet Vent Section View of Mask Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy System Features Outlet Vent Breathing Cycle Step 3: As the subject exhales, the vents between the plenum and mask close to prevent contamination of the next batch of vapour. The exhaled breath leaves the mask via the outlet vents positioned directly adjacent to the nostrils. Section View of Mask Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy Configuration Benefits 1. Jet Nebuliser (with Oxygen) Treatment Delivery O2 • The Jet Nebuliser facilitates rapid delivery of drugs and serums such as Autologous Conditioned Serum (ACS) from MediVet Labs. • Treatment is accelerated via simultaneous oxygen delivery. The benefits of this include: • Minimising the release of Hydrocortisone (stress hormone). Hydrocortisone can inhibit beneficial immune responses. • Maximising the oxygen processing capacity of cell mitochondria which boosts cell activity. • The click style oxygen regulator supplied with the MPTS 360 is the most robust type on the market and easiest to use with set flow rates to match all therapy requirements. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy Configuration Benefits 2. Ultrasonic Nebuliser Treatment Delivery • The Ultrasonic Nebuliser generates the ideal aerosol particle size of a wide range of drugs including, but not limited to saline, bronchodilators, corticosteroids and antibiotics. • An 8mL reservoir and AA battery power pack supports up to 2 hours continuous treatment. Standard treatment time is 15 mins • The nebuliser is specially designed to facilitate easy cleaning to ensure optimum therapy can always be achieved. Complete cleaning after every use is essential. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Therapy Configuration Benefits 3. Metered Dose Inhaler (MDI) Treatment Delivery • MDIs are used for most day-to-day medications prepared by veterinarians. The multi-purpose inlet is perfectly sized and positioned to allow use of these devices between therapies / training sessions without removing the mask or carrying the chambers etc. usually required for MDI administration. • The MDI seals into the plenum chamber to permit administration of controlled dosages. This takes advantage of the superior mask seal and vapour entrainment to prevent wastage of medication. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Therapy System Summary The MPTS 360 is compatible with almost all therapy delivery options available on the market today. The MPTS 360’s unique design features enhance medication delivery and animal comfort to maximise therapy outcomes. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Training System Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training System Features • The MPTS 360 is the only mask system on the market designed to meet the needs of trainers using both hypoxic (low oxygen) and hyperoxic (high oxygen) training. • These training principles deliver a physiological response by working a particular body system at a target arterial blood oxygen concentration (SpO2). • Hypoxic training (SpO2 80-85%) typically allows the trainer to target development of the respiratory and cardio systems. • Hyperoxic training (SpO2 >95%) typically allows the trainer to target development of the muscular system. • These conditions are applied during treadmill and hydrotherapy training. Hyperoxic conditions are also used to aid recovery after training or an event. Front View Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training System Features MPTS 360 Mask Click Style Regulators Supplemental Gas: N2 for Hypoxic Training O2 for Hyperoxic Training Treadmill or Hydro Trainer O2 N2 • The MPTS is the latest technology solution for achieving hypoxic / hyperoxic conditions. • The trainer places the mask over the animal’s face and connects it to the gas source required for the session e.g. N2 gas for a hypoxic training session. • For Hypoxic training conditions, supplemental N2 gas is used. • For Hyperoxic training conditions, supplemental O2 gas is used. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training System Features • The trainer is responsible for developing a training regime in consultation with their veterinarian to suit: • The fitness of the animal • Available training facilities • Training objectives. • A typical training regime will involve adjustment of the supplemental gas level and training workload based on the animal’s physiological response (e.g. SpO2 or lactate level) to a given exercise intensity as measured by heart rate. • Examples of training regimes include: • Intermitted hypoxic training based on a standard chart of Nitrogen gas rates. • Short bursts of high intensity exercise on a treadmill / water walker at high levels of hypoxia / hyperoxia monitored by blood gas analysis or pulse oximeter between bursts. • Refer to www.MPTS360.com for more information Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training System Features • The MPTS 360 is design features make it the perfect platform for hypoxic or hyperoxictraining: • Supplemental gas is mixed with air in the plenum before being delivered on demand to the animal. Combined with the high performance mask seal, this maximises control of the gas mix and greatly reduces gas wastage vs. other training systems on the market today. • The close fitting mask profile minimises CO2 rebreathing to maximise exercise efficiency and animal comfort. • The Hi-Flow vents (largest vents on the market) ensures the animal can draw the breath comfortably at the high respiratory rates needed for high intensity exercise. Exhaust Vent Supplemental Gas Inlet Multi-fit seal Dividing Vent Integrated Mixing Plenum Low Profile Mask Inlet Vent Section View of Mask Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training Configuration Benefits 1. Hypoxic Training (Low Oxygen) • The multi purpose training system may be used to support hypoxic training. Hypoxic Training offers significant benefits including: • Deeper breathing – Engages greater lung volume for oxygen transfer • Increased Haemoglobin – Required for oxygen transport • Increased Bisphosphoglyceric acid 2-3 – Aids O2 release into tissues • Release of Bicarbonate into bloodstream – Prevents Hyperventilation • Production of Citrate Synthase – Aids O2 release into tissues • Increase in Myoglobin – Increases O2 storage in muscle tissue • Right Ventricle Hypertrophy – Improved blood transport between heart and lungs Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training Configuration Benefits 2. Hyperoxic Training (High Oxygen) • The multi purpose training system may be used for to support hyperoxic training. • Hyperoxic conditions allow longer and more frequent bouts of higher intensity training for increased strength and endurance by: • Preventing the decrease in arterial oxygen concentration during high intensity exercise which causes fatigue and the formation of lactic acid. • Increasing the rate of replenishment for arterial oxygen concentration during recovery for faster dissipation of lactic acid. • Reducing the amount and duration of release of Hydrocortisone (stress hormone). • Increasing the amount of oxygen supplied to cell mitochondria, prolonging aerobic metabolism by the cell for longer, more intense training sessions at lower risk of tissue damage. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360Training Configuration Benefits 3. Oxygen Delivery • The multi purpose training system may be used to supply oxygen therapy. Oxygen therapy offers significant benefits including: • Managing the release of Hydrocortisone (stress hormone) which at prolonged high levels reduces the effectiveness of the immune system. • Increasing the oxygen holding and maximising the processing capacity of cell mitochondria (oxygen banking) which allows prolonged aerobic activity and helps prevent tissue damage. • Increased recovery rate after strenuous exercise including: hormone balancing, replenishment of fuel stores (including phosphagen, ATP, creatine and anabolism), cellular repair and the dissipation of lactic acid. • The mask system can also be used to supply medical gas to reduce CO absorption during transport in a horse box. • High hydrocortisone can also prematurely trigger a splenic dump (best reserved for just before an event) where the body temporarily boosts blood supply by accessing reserves from the spleen. • Inhaled CO greatly reduces respiratory efficiency by displacing oxygen in the blood. CO absorbed during road transport has been shown to reduce aerobic performance for days after exposure. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Training System Summary The MPTS 360 is the only system on the market designed with the help of leading exercise scientists to facilitate effective hypoxic and hyperoxic training of horses and camels. Delivery of hypoxic / hyperoxic training outcomes is simple and effective with the supplemental gas training technique. Manage Carbon Monoxide (CO) and stress levels in your animals before an event and take advantage of rapid recovery afterwards facilitated by oxygen therapy. Product Overview – Multi-Purpose Training System (MPTS 360)

MPTS 360 Product Summary • The MediVet MPTS 360 has been developed to meet all the therapy and training needs of the professional animal trainer. • The MPTS 360 combines all conceivable therapy and training options in an effective, easy to use package. • The MPTS 360 has been carefully designed and rigorously tested to ensure usability, animal comfort and maximum effectiveness. • The MPTS 360 is the Ultimatetherapy delivery system supporting: • Ultrasonic Nebuliser Treatment Delivery • Jet Nebuliser (with Oxygen) Treatment Delivery • Metered Dose Inhaler (MDI) Treatment Delivery • The MPTS 360 is the Ultimate training system designed to support: • Hypoxic (Altitude) Training • Hyperoxic (high oxygen) Training • Oxygen assisted recovery • Refer to www.MPTS360.com for more information Product Overview – Multi-Purpose Training System (MPTS 360)

Product Overview Multi-Purpose Training System MPTS 360