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R1-R10 : Dr. Example Research

R1-R10 : Dr. Example Research. Photo. Research Title. Research area. Write down your research details etc. Put any figures relating to your work. fscixxx@ku.ac.th. Our work shows…………………………. The main goal of this project is to……………………………………………………………. Research title. Research area.

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R1-R10 : Dr. Example Research

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  1. R1-R10 : Dr. Example Research Photo Research Title Research area Write down your research details etc Put any figures relating to your work fscixxx@ku.ac.th Our work shows…………………………. The main goal of this project is to……………………………………………………………. Research title Research area Put any figures relating to your work Our work shows…………………………. The aim of this project is to……………………………………………………

  2. R4: Assist. Prof. NonlawatBoonyalai Plasmodium aspartic proteases (Plasmepsins) as antimalarial drug targets Antimalarial Drug Discovery: Plasmodium export element (PEXEL) signal RxLxE/D/Q downstream of the signal peptide is known to export proteins to the erythocyte. PEXEL motif is proteolytically cleaved after the RxL in the ER, to generate xE/D/Q at the N-terminus. fscinwb@ku.ac.th PMV is necessary for parasite viability and is the protease responsible for cleavage of the PEXEL sequence and ensuring protein export. The main goal of this project is to design potent small molecule PM V inhibitors that will help to further probe the biology of the malaria parasite’s export pathway and, ultimately, to generate a new antimalarial drug. Inhibitory mechanism study of human Topoisomerase II by naphthoquinone derivatives Anticancer Drug Discovery: IC50 = 15.16 μM IC50 = 1.76 μM The objective of this project is to develop an understanding of the binding mode of drug by investigating the interactions, complex structures and biophysical properties of Topoisomerase II and rhinacanthins derivatives. We are also interested in evaluating other Topoisomerase II inhibitors.

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