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Realistic modeling the cerebellar cortex

OPEN SOURCE BRAIN. Sergio Solinas , Egidio D’Angelo University of Pavia IRCCS C. Mondino Alghero 13-15 May 2013. Realistic modeling the cerebellar cortex. 1958. “a lattice” 55 years later. OSB website . Parasagittal organization Golgi cell axon.

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Realistic modeling the cerebellar cortex

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  1. OPEN SOURCE BRAIN Sergio Solinas, Egidio D’Angelo University of Pavia IRCCS C. Mondino Alghero 13-15 May 2013 Realisticmodeling the cerebellarcortex

  2. 1958

  3. “a lattice” 55 yearslater OSB website

  4. ParasagittalorganizationGolgi cellaxon Barmack & Yakhnitsa J. Neurosci. 2008

  5. ParasagittalorganizationMossyfiber branching Wu et al. J. Comparative Neurology 1999

  6. Lattice arrangement Purkinjecell dendriticfields Stellate cell axonalfield Golgi cell axonalfield Parallel fibers Golgi cell dendriticfield Pellionisz & SzentágothaiBrain Research 1973

  7. Network picture from otto

  8. Input of the cerebellarcortex Convey channel: Cerebral cortex Sensory nuclei

  9. Center/ surround effect Spot scale 200 µm

  10. Parallelffiber scale 2 mm: Lateralinhibition

  11. Collaborative development Sheffield: tests and analysisprocedures Amrita: LFP reconstruction & Multicompartmenteal GRC model

  12. Field Programmable Gate Array (FPGA) PhDThesis Alessandra Majani Hart beat discrimination F1 engine monitor NEURON simulator

  13. FPGA simulator Single compartment model of Cerebellargranulecell (D’Angelo et al. 2001, Solinas et al .2010)

  14. FPGA simulator

  15. Neurophysiology Lab in Pavia Brain Connectivity Center IRCCS C. Mondino Egidio D’Angelo Francesca Prestori Lisa Mapelli Daniela Gandolfi (Modena) Jonathan Mapelli (Modena) Francesca Locatelli Luigi Congi Ramakrishnan K. B. Licia de Propris Martina Sgritta Martina Pagani Paolo Pozzi JesusGarrido Stefano Masoli SathyaaSubramaniyam Timoteo Colnaghi Fulvia Palesi Gloria Castellazzi Jessica Monaco Stefano Casali Alessandra Majani Irene Solinas Leda Ruggeri

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