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Pregnenolona , Cannabis - ul si receptorii canabinozi

Pregnenolona , Cannabis - ul si receptorii canabinozi. Cristiana Trandafir. Substanțe care protejează creierul de efectele drogurilor. Pregnenolona. Prohormon : progesteroni, mineralocorticoizi, glucocorticoizi, androgeni, estrogeni, steroizi neuroactivi Anxiolitic Neuroprotector

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Pregnenolona , Cannabis - ul si receptorii canabinozi

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  1. Pregnenolona,Cannabis-ulsireceptoriicanabinozi Cristiana Trandafir Substanțe care protejează creierul de efectele drogurilor

  2. Pregnenolona • Prohormon: progesteroni, mineralocorticoizi, glucocorticoizi, androgeni, estrogeni, steroizi neuroactivi • Anxiolitic • Neuroprotector • Favorizează mielinizarea • Stimuleaza functia cognitiva și memoria • Pregnenolona sulfat: eliberare insulina

  3. Receptorul CB1

  4. THC* și pregnenolona HSL = hormone-sensitive lipase Erk ½ = extracellular signal-regulated kinases ½ StAR= steroidogenic acute regulatory protein Negative feedback *THC= tetrahidrocannabinol

  5. EfecteLE PREGNENOLONEI • Locomoție • Temperatură • Catalepsie • Analgezie • Aport alimentar • Tulburări cognitive/ de memorie • Adicție

  6. concluzii Mecanism de acțiune ↓ Medicamente care activeaza CB1R in absentacanabinoidului

  7. Mersi!

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