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CNS Sequence

CNS Sequence. CNS Histology March 9, 2009. Spinal cord. Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic (S2-4) neurons DRG: Sensory (pseudounipolar) neurons

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CNS Sequence

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  1. CNS Sequence CNS Histology March 9, 2009

  2. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic (S2-4) neurons DRG:Sensory (pseudounipolar) neurons Autonomic ganglia: Post ganglionic neurons with unmyelinated axons. Sympathetic: paravertebral ganglia Parasympathetic: In organs

  3. 66a Thoracic Spinal Cord Dorsal median sulcus Dorsal horn Dorsal nucleus of Clarke Lateral horn Ventral horn Ventral median fissure

  4. 66a Thoracic Spinal Cord Neurons in Lateral Horn Neurons in Ventral Horn (preganglionic sympathetic neurons of intermediolateral cell column) (motor neurons)

  5. Thoracic cord dorsal horn: spinocerebellar neurons of Clarke’s nucleus (relay proprioceptive input up to cerebellar cortex: e.g. from muscle spindle  DRG  spinocerebellar neuron  cerebellum)

  6. Thoracic cord: dorsal horn neurons (interneurons) short projections to other neurons at same level or nearby spinal level

  7. #65-1N Spinal cord and DRG Dorsal horn Lateral horn Ventral horn Dorsal root ganglion (DRG)

  8. 65-1N Motor neurons, glial cells and neuropil Glial cells Neuropil

  9. Dorsal root ganglion cells

  10. Motor and Sensory Neurons(Multipolar) (Pseudounipolar)

  11. Brain Cerebrum Sulcus (sulci) Gyrus (gyri) 3rd ventricle Cerebellum 4th ventricle Pons Medulla oblongata

  12. Cerebrum and Cerebellum 76b 77

  13. #77 Cerebellum #76b Cerebrum C: Cortex of gray matter W: White matter C C C W W W

  14. #77 Cerebellum Cortex White matter

  15. #77 Cerebellum ML GL WM Purkinje neurons (cells)

  16. #77a Cerebellar Cotex

  17. #76 Cerebrum White matter Cortex of gray matter

  18. #76 Cerebral cortex Ross and Pawlina, p.311

  19. CerebellumCerebrum C: Cortex of gray matter W: White matter Purkinje cells (neurons) C C Pyramidal cells (neurons) W W

  20. #NP004N Hippocampal regionCA: Cornus ammonis ependymal cells of choroid plexus (cuboidal, eosinophilic: produce CSF) choroid plexus CA3 CA2 “typical” ependymal cells (columnar, lining cells) Hippocampus CA4 (hilus) Dentate gyrus CA1

  21. 3 layers of Hippocampal region (CA1-CA3) Polymorphic layer (nerve fibers, interneuron cell bodies) Pyramidal cell layer Molecular layer (dendrites of pyramidal cells) Pyramidal cells

  22. 3 layers of Dentate gyrus Molecular layer Molecular layer (dendrites of granule cells) Granule cell layer (neurons) Polymorphic layer Polymorphic layer (interneurons)

  23. #74 Sympathetic ganglion cells #75 Parasympathetic ganglion cells Seminal vesicle

  24. Sensory and Autonomic Neurons(DRG) (Parasympatheitc)

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