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Avian infections

Viral infections of respiratory tract. Newcastel disease virusAvian influenzaAvian infectious bronchitis virusAvian laryngotracheitis disease virusAdenoviruses. Avian infectious bronchitis virus. Many strains (differ in antigenic properties and virulence) - mutations and recombinationAffects

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Avian infections

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    1. Avian infections

    2. Viral infections of respiratory tract Newcastel disease virus Avian influenza Avian infectious bronchitis virus Avian laryngotracheitis disease virus Adenoviruses

    3. Avian infectious bronchitis virus Many strains (differ in antigenic properties and virulence) - mutations and recombination Affects young animals from 3 weeks Maternal antibodies control infection for 3 weeks Suffocation, cough, sternutation, urate plug, drop of lay, clinical signs last for 10 14 days

    4. Avian infectious bronchitis virus Horizontal spread Rapid spread high concentration of animals Vertical transmission not demonstrated Virus replicates in epithelial a subepithelial cells of repiratory tract and kidney (nefropathogenic strains) Virus persistence and long term shedding

    5. Avian infectious bronchitis virus - diagnostics Tracheal swabs till 14 days in chicken, 7-10 days in older, 2-3 weeks in nefropat. strains Virus isolation in acute phase of the disease CAM (2-3 passages) tracheal explantates (ciliostasis in 2-3 days Variant strains and Ag mutants sentinel SPF animals

    6. Avian infectious laryngotracheitis virus Acute disease of chicken, pheasants (3-9 month) Respiration problems, bloody mucous secretion Conjunctivitis - panophtalmitis Mild - peracute disease Antigenic uniformity, strains differ in virulence Impact of environment (iritation of resp.tract, low temperature, concurrent infections)

    7. Avian infectious laryngotracheitis virus Virus latency in infected and vaccinated animals Rezidual pathogenicity of vaccine strains Cell immunity non-transmissible to the newborns

    8. Avian infectious laryngotracheitis virus Samples: 4-6 living animals trachea, larynx - chilled, not frozen Diagnostics I.N. inklusions - trachea IF test trachea Izolation on EE (CAM), IFA identification Differentiation of vaccine and field strains by REA

    9. Newcastel disease virus Different pathotypes of the virus Velogenic (viscerotropic and neurotropic) Mezogenic Lentogenic Serologically unique Respiratory signs in velogenic and mezogenic strains

    10. Newcastel disease virus Velogenic strains respiratory signs (edema of the neck, head), diarhea, neurological signs, bleeding, almost 100% mortality

    11. Newcastel disease virus Diagnostics Izolation: embryonated eggs Detection: hemagglutination, PCR Samples: lungs, spleen, brain, trachea. Indirect detection: hemagglutination inhibition test (HIT) a virus neutralizing test (VNT)

    12. THE RESPIRATORY TRACT

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